Sigma Receptor - GPCR/G protein

Cat.No. Product Name Information

BCC4190 S1RA hydrochloride S1RA hydrochloride (E-52862 hydrochloride) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM).

BCC5902 (+)-Igmesine hydrochloride

BCC6928 (+)-SK&F 10047 hydrochloride (+)-SK&F 10047 hydrochloride

BCC6674 BD 1008 dihydrobromide

BCC6863 BD 1047 dihydrobromide BD-1047 (dihydrobromide) is a selective functional antagonist of sigma-1 receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.

BCC4304 Siramesine Siramesine(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.

BCC7573 NE 100 hydrochloride

BCC7429 PD 144418 oxalate PD 144418 is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki values of 0.08 nM and 1377 nM for σ1 and σ2 respectively), devoid of any significant affinity for other receptors, ion channels and enzymes. PD 144418 shows potential antipsychotic activity. PD 144418 oxalate

BCC6784 N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide

BCC6777 4-IBP 4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) . 4-IBP

BCC6339 SA 4503 dihydrochloride Cutamesine dihydrochloride (SA4503 dihydrochloride; AGY94806 dihydrochloride) is a potent Sigma 1 receptor agonist with an IC50 of 17.4 nM in guinea pig brain membranes.

BCC7411 PB 28 dihydrochloride

BCC5662 IPAG IPAG

BCC6723 4-PPBP maleate

BCC6832 BD 1063 dihydrochloride BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.

BCC5657 L-693,403 maleate

BCC7450 TC 1 TC 1

BCC6708 PRE-084 hydrochloride PRE-084 hydrochloride is a high affinity, selective σ1 agonist, has an IC50 of 44 nM in the sigma receptor assay.

BCC7090 Rimcazole dihydrochloride

BCC4189 S1RA S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM). S1RA

BCC7796 (±)-PPCC oxalate

BCC5664 Metaphit

BCC6812 DTG Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor). DTG

Products for Sigma Receptor