Actin
Actin is a family of globular multi-functional proteins that form microfilaments. It is found in essentially all eukaryotic cells (the only known exception being nematode sperm), where it may be present at a concentration of over 100 μM. An actin protein's mass is roughly 42-kDa, with a diameter of 4 to 7 nm, and it is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. It can be present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential for such important cellular functions as the mobility and contraction of cells during cell division.
Products for Actin
- Cat.No. Product Name Information
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BCN5049
Cytochalasin D Disrupts actin filament function
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BCC5866
187-1, N-WASP inhibitorN-WASP inhibitor; inhibits actin assembly
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BCC6088
CK 666Arp2/3 inhibitor; inhibits actin polymerization
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BCC6162
SMIFH2FH2 domain inhibitor; prevents actin nucleation
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BCC6347
CK 869Arp2/3 inhibitor; inhibits actin polymerization
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BCC7485
JasplakinolideStabilizes F-actin; promotes actin polymerization
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BCC7830
Latrunculin AInhibitor of actin assembly and polymerization
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BCC7934
WiskostatinN-WASP inhibitor; inhibits Arp2/3 activation
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BCC7945
PhalloidinPromotes actin polymerization