MMP

Matrix metalloproteinases (MMPs) are a family of zinc-dependent neutral endopeptidases, generally consisting of a single peptide, a propeptide domain, a catalytic domain with a highly conserved zinc-binding site and a haemopexin-like domain, that catalyze the degradation of all components of the extracellular matrix. Multiple studies have shown that MMPs are overexpressed in malignant tumor and involved in the process of tumor growth, invasion and metastasis. Thus, synthetic and naturally occurring MMP inhibitions have been investigated as anti-cancer agents for the treatment of a variety of cancers, which are divided into three pharmacologic categories, including collagen peptidomimetics and nonpeptidomimetics, tetracycline derivatives and bisphosphonates.

Products for MMP

  1. Cat.No. Product Name Information
  2. BCC1223 Batimastat (BB-94)Potent, broad spectrum MMP inhibitor
  3. BCC1502 CTS-1027MMPs inhibitor
  4. BCC2075 Batimastat sodium saltAnticancer drug
  5. BCC2118 MarimastatBroad spectrum MMP inhibitor
  6. BCC2119 GM 6001Broad spectrum MMP inhibitor
  7. BCC2120 NSC 405020Inhibitor of MT1-MMP; antitumor
  8. BCC2370 ARP 100Selective inhibitor of MMP-2
  9. BCC2371 ARP 101Inhibitor of MMP-2
  10. BCC2372 CL 82198 hydrochlorideSelective MMP-13 inhibitor
  11. BCC2373 CP 471474Broad spectrum MMP inhibitor
  12. BCC2374 GI 254023XSelective ADAM10 metalloprotease inhibitor
  13. BCC2375 ONO 4817Broad spectrum MMP inhibitor
  14. BCC2376 PD 166793Broad spectrum MMP inhibitor
  15. BCC2377 Ro 32-3555Potent, collagenase-selective MMP inhibitor
  16. BCC2378 UK 356618Potent and selective MMP-3 inhibitor
  17. BCC2379 UK 370106Highly selective MMP-3 and MMP-12 inhibitor
  18. BCC2380 WAY 170523MMP-13 inhibitor,potent and selective
  19. BCC3772 Doxycycline HClTetracycline antibiotic;MMP inhibitor;cell selection reagent
  20. BCC6488 DC_AC50Selective Atox1 and CCS inhibitor

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