Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5995 | Squalene |
| Squalene, a naturally occurring substance found in plants, animals and humans, is a component of some adjuvants that is added to vaccines to enhance the immune response.Squalene shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Squalene can significantly suppress colonic aberrant crypt foci (ACF) formation and crypt multiplicity strengthens the hypothesis that squalene possesses chemopreventive activity against colon carcinogenesis. | |
| BCN6000 | Adenanthin |
| 1. Adenanthin has bacteriostatic activity. 2. Adenanthin has antiinflammatory activity. 3. Adenanthin has antitumour activity . 4. Adenanthin is a novel NF-κB and nucleophilic cysteines inhibitor. 5. Adenanthin has antileukemic activity through targeting peroxiredoxin I/II. 6. Adenanthin can serve as the development of Prx I– and Prx II–targeted therapeutic agents. | |
| BCN6019 | Caryophyllene oxide |
| Caryophyllene oxide, an oxygenated terpenoid existed in many plant essential oil, is well known as preservative in food, drugs and cosmetics with antifungal, acaricidal, anti-inflammatory, anti-carcinogenic, significant central as well as peripheral analgesic and skin penetration enhancing properties. Caryophyllene Oxide and lupenone have synergistic effect against Trypanosoma cruzi. It inhibited growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways, ROS-mediated MAPKs activation, and via modulation of 15-LOX. | |
| BCN6024 | Ganoderiol F |
| Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS)-induced nitric oxide (NO) production. | |
| BCN6037 | Galanolactone |
| 1. Galanolactone shows cytotoxic activity . 2. Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors. 3. Galanolactone exerts anti-obesity effect through down regulation of adipogenic transcription factors and adipogenic marker genes. 4. Galanolactone has inhibit nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM. | |
