Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6276 | Dryocrassin ABBA |
| 1. Orally administered dryocrassin ABBA provides mice protection against avian influenza virus H5N1 by inhibiting inflammation and reducing virus loads; dryocrassin ABBA is a potential novel lead compound which has antiviral effects on amantadine-resistant avian influenza virus H5N1 infection. 2. Dryocrassin ABBA can significantly suppress tumor growth, without major side effects; suggests that it may induce apoptosis in human hepatocellular carcinoma cells through a caspase-mediated mitochondrial pathway. | |
| BCN6279 | Plantamajoside |
| Plantamajoside has antibacterial, antioxidant, anti-tumor, anti-inflammatory and anti-skin photoaging effects, it has protective activities against Cadmium-induced renal injury. Plantamajoside ameliorates lipopolysaccharide-induced acute lung injury via suppressing NF-κB and MAPK activation, it can inhibit UVB and advanced glycation end products‐induced MMP-1 Expression by suppressing the MAPK and NF‐ĸB pathways in HaCaT cells, and attenuate the upregulation of receptor for AGEs (RAGE) by glycer-AGEs with UVB irradiation. | |
| BCN6281 | Crotonoside |
| Crotonoside is one compound of an antitumor and immunity-regulating pharmaceutical composition of traditional Chinese medicine. | |
| BCN6283 | Amentoflavone |
| Amentoflavone is a novel natural inhibitor of human Cathepsin B(CatB), which has antifungal , antioxidant, antiviral, antidiabetic, and neuroprotective activities, it stimulates apoptosis in HSFBs and inhibits angiogenesis of endothelial cells, it is a promising molecule that can be used in hypertrophic scar treatment. Amentoflavone regulated β-catenin and caspase-3 expressions, and inhibited NF-κB signal transduction pathways. | |
| BCN6284 | Pseudolaric Acid B |
| Pseudolaric Acid B has dual antiangiogenic, anti-fungal, anti-fertility, anti-inflammatory, immunomodulatory and pro-apoptosis effects. Pseudolaric Acid B reversed the multidrug resistance of gastric neoplasm to chemotherapy drugs by downregulating the Cox-2/PKC-α/P-gp/mdr1 signaling pathway, it suppressed T lymphocyte activation through inhibition of NF-κB and p38 signaling pathways. | |
