Products with Anticancer Bioactivity

Explore BioCrick products associated with Anticancer biological activity, including catalog numbers, product names and available bioactivity information.

Anticancer Bioactivity Products

Cat. No. Product Name
BCN6348 Pseudohypericin
Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS. Pseudohypericin can inhibit LPS-stimulated PGE2 and NO in mouse macrophages by potentiating suppressor of cytokine signaling 3 (SOCS3) expression, it has anti-tumor potential.
BCN6350 Sanggenone C
1. Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenone C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.
BCN6354 Sennidin A
1. Sennidin A in combination with necrosis inducing drugs/therapies may generate synergetic tumoricidal effects on solid malignancies by means of primary debulking and secondary cleansing process. 2. Sennidin A stimulates glucose incorporation in the phosphatidylinositol 3-kinase (PI3K)- and Akt-dependent in rat adipocytes, but in the IR/IRS1-independent manner. 3. Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 uM.
BCN6356 Sinensetin
Sinensetin is a polymethoxylated flavonoids in citrus fruit, as a novel antiangiogenesis agent, has potential for anti-carcinogenesis, antitumor, and cardiovascular protective activities. Sinensetin has antioxidative effect and has anti-inflammatory by regulating the protein level of inhibitorκB-α, it enhances adipogenesis and lipolysis by increasing cAMP levels in adipocytes.
BCN6457 Lanatoside C
1. Lanatoside C, a cardiac glycoside, is an anti-arrhythmic agent. 2. Lanatoside C acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells. 3. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya and Sindbis virus as well as the human enterovirus 71, suggest that lanatoside C possesses broad spectrum antiviral activity against several groups of positive-sense RNA viruses.

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