Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4238 | 4',5,7-Trihydroxy-6-prenylflavone |
| 1. 6-Prenylapigenin(4',5,7-Trihydroxy-6-prenylflavone) shows potent inhibitory activity on melanin formation, it may be potential sources for skin whitening agents. 2. 6-Prenylapigenin shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines. | |
| BCN4290 | Acetylursolic acid |
| Acetylursolic acid shows significant cytotoxic activities, and shows suppression of the SOS-inducing activity of mutagenic heterocyclic amine, Trp-P-1. 3β-Acetylursolic acid can reduce parasitaemia against Plasmodium berghei. | |
| BCN4293 | Hispidone |
| 1. Hispidone shows potent cytotoxic activity against P388 and KB cells. | |
| BCN4303 | Obacunone |
| Obacunone is a novel activator of Nrf2, which exhibits anti-cancer, anti-inflammatory, antivirulence, insecticidal, anti-proliferative and anti-aromatase activities. Obacunone stimulates muscle hypertrophy and prevents obesity and hyperglycemia, and that these beneficial effects are likely to be mediated through the activation of TGR5 and inhibition of PPARγ transcriptional activity. Obacunone significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM, and it also inhibits the p38 MAPK signaling pathway. | |
| BCN4307 | Cedrusin |
| 1. Cedrusin shows a cytotoxic effect on A375 and HeLa cells. | |
