Products with Cytotoxic bioactivity

Cat.No. Product Name
BCN4116 Tamarixetin
1. Tamarixetin has cytotoxic against leukemia cells and in particular P-glycoprotein- overexpressing K562/ADR cells, it inhibits proliferation in a concentration- and time-dependent manner, induces apoptosis and blocked cell cycle progression at G2 -M phase. 2. Tamarixetin has vasodilator effects in rat isolated vessels.
BCN4130 Isobonducellin
1. Isobonducellin exhibits potent cytotoxic activity in Jurkat and HepG2 cells, while moderate growth inhibition against Colon205 cells.
BCN4161 Ursonic acid
Ursolic acid, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways. Ursonic acid has antiviral activity against Herpes simplex virus types I and II in vitro; it also could be used in preparation of depression treatment medicine.
BCN4182 Longistylin C
1. Longistylin A and longistylin C show some cytotoxic effects, with IC(50) values of 0.7-14.7 microM against the range of cancer cell lines. 2. Longistylin A and longistylin C, and betulinic acid show a moderately high in vitro activity against the chloroquine-sensitive Plasmodium falciparum strain 3D7.
BCN4193 Sendanolactone
1. Sendanolactone possesses moderate cytotoxic activity against KB cell lines.

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