Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3689 | Lusianthridin |
| 1. Lusianthridin shows appreciable cytotoxicity against human lung cancer cell lines. 2. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. | |
| BCN3692 | Sanggenol L |
| 1. Sanggenol L induces apoptosis via caspase activation and inhibition of NF-κB/IκBα phosphorylation as a potent chemotherapeutic agent for ovarian cancers. 2. Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF). | |
| BCN3705 | Inulanolide A |
| 1. Inulanolide A has potent cytotoxicity. 2. Inulanolide A is a novel NFAT1 and MDM2 dual targeting agent and may be a clinical candidate for breast cancer therapy. | |
| BCN3713 | Dihydrosanguinarine |
| Dihydrosanguinarine has antifungal and anticancer activity.Dihydrosanguinarine at concentrations from 5 microM induced primarily necrosis, whereas apoptosis occurred at 10 microM and above. Dihydrosanguinarine has potential application in the therapy of serious infection caused by I. multifiliis. | |
| BCN3714 | Norsanguinarine |
| 1. Norsanguinarine shows significant cytotoxic activities (ED (50) values < 4 microg/ml) against P-388, KB16, A549, and HT-29 cell lines. 2. Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. | |
