NorsanguinarineCAS# 522-30-5 |
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| Cas No. | 522-30-5 | SDF | Download SDF |
| PubChem ID | 97679 | Appearance | Powder |
| Formula | C19H11NO4 | M.Wt | 317.1 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | C1OC2=C(O1)C3=CN=C4C(=C3C=C2)C=CC5=CC6=C(C=C54)OCO6 | ||
| Standard InChIKey | CNXVDVMAYXLWPD-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C19H11NO4/c1-2-12-11-3-4-15-19(24-9-21-15)14(11)7-20-18(12)13-6-17-16(5-10(1)13)22-8-23-17/h1-7H,8-9H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Chelidonium majus
| Description | 1. Norsanguinarine shows significant cytotoxic activities (ED (50) values < 4 microg/ml) against P-388, KB16, A549, and HT-29 cell lines. 2. Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. |
| Targets | Antifection |
Norsanguinarine Dilution Calculator
Norsanguinarine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1536 mL | 15.7679 mL | 31.5358 mL | 63.0716 mL | 78.8395 mL |
| 5 mM | 0.6307 mL | 3.1536 mL | 6.3072 mL | 12.6143 mL | 15.7679 mL |
| 10 mM | 0.3154 mL | 1.5768 mL | 3.1536 mL | 6.3072 mL | 7.8839 mL |
| 50 mM | 0.0631 mL | 0.3154 mL | 0.6307 mL | 1.2614 mL | 1.5768 mL |
| 100 mM | 0.0315 mL | 0.1577 mL | 0.3154 mL | 0.6307 mL | 0.7884 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antifungal activity of the alkaloids from Eschscholzia californica.[Pubmed:19649736]
Folia Microbiol (Praha). 2009;54(3):204-6.
The isoquinoline alkaloids hunnemanine and Norsanguinarine have been isolated from methanolic extract of the whole plant of Eschscholzia californica. These two alkaloids were checked for their antifungal activity against phytopathogenic fungi Alternaria melongenae, A. brassicola, A. brassicae, Curvularia lunata, C. maculans, Helminthosporium pennisetti, H. oryzae, H. turcicum, Fusarium undum and F. lini. Hunnemanine exhibited 100 % inhibition of spore germination of A. brassicae, H. pennisetti and F. lini at 1000 ppm whereas Norsanguinarine exhibited 100 % inhibition of A. brassicicola and C. maculans at this concentration.
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