Lamalbid

CAS# 52212-87-0

Lamalbid

Catalog No. BCN3750----Order now to get a substantial discount!

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Quality Control of Lamalbid

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Chemical structure

Lamalbid

3D structure

Chemical Properties of Lamalbid

Cas No. 52212-87-0 SDF Download SDF
PubChem ID 21637592 Appearance Powder
Formula C17H26O12 M.Wt 422.4
Type of Compound Iridoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name methyl (1S,4aS,5S,6S,7R,7aS)-5,6,7-trihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylate
SMILES CC1(C2C(C(C1O)O)C(=COC2OC3C(C(C(C(O3)CO)O)O)O)C(=O)OC)O
Standard InChIKey HHDWDLBSGSYIQQ-GNDDPXJISA-N
Standard InChI InChI=1S/C17H26O12/c1-17(25)8-7(10(20)13(17)23)5(14(24)26-2)4-27-15(8)29-16-12(22)11(21)9(19)6(3-18)28-16/h4,6-13,15-16,18-23,25H,3H2,1-2H3/t6-,7-,8-,9-,10+,11+,12-,13+,15+,16+,17-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Lamalbid

The herbs of Lamium barbatum

Biological Activity of Lamalbid

DescriptionStandard reference

Protocol of Lamalbid

Structure Identification
Phytochemistry. 2010 Oct;71(14-15):1690-4.

Biosynthesis of the iridoid glucoside, lamalbid, in Lamium barbatum.[Pubmed: 20656306]


METHODS AND RESULTS:
The biosynthesis of the iridoid glucoside Lamalbid in Lamium barbatum, a plant species in the Lamiaceae, was investigated by administrating (13)C-labeled intermediates of MVA and MEP pathways, respectively. The results demonstrated that [3,4,5-(13)C(3)]1-deoxy-D-xylulose 5-phosphate could be incorporated into Lamalbid, whereas the incorporation of [2-(13)C(1)]mevalonolactone was not observed.
CONCLUSIONS:
Based on the (13)C labeling pattern of Lamalbid and the incorporation data, we deduce that the iridoid glucoside in L. barbatum is biosynthesized through the MEP pathway, whereas the classic MVA pathway is not utilized.

Zhongguo Zhong Yao Za Zhi. 1999 Jan;24(1):40-1, 64.

Iridoid glycosides from Pedicula dicora Franch.[Pubmed: 12078153]

To study the components in the root of Pedicula dicora.
METHODS AND RESULTS:
Column chromatography with silica gel and polyamide was employed for the isolation and purification of ingredients. The structures were elucidated by spectral method. Three iridoid glycosides were obtained and elucidated as mussaenoside, shanzhiside methyl ester and Lamalbid.
CONCLUSIONS:
All the three compounds were separated from P. dicora for the first time.

Lamalbid Dilution Calculator

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Preparing Stock Solutions of Lamalbid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3674 mL 11.8371 mL 23.6742 mL 47.3485 mL 59.1856 mL
5 mM 0.4735 mL 2.3674 mL 4.7348 mL 9.4697 mL 11.8371 mL
10 mM 0.2367 mL 1.1837 mL 2.3674 mL 4.7348 mL 5.9186 mL
50 mM 0.0473 mL 0.2367 mL 0.4735 mL 0.947 mL 1.1837 mL
100 mM 0.0237 mL 0.1184 mL 0.2367 mL 0.4735 mL 0.5919 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Lamalbid

Biosynthesis of the iridoid glucoside, lamalbid, in Lamium barbatum.[Pubmed:20656306]

Phytochemistry. 2010 Oct;71(14-15):1690-4.

The biosynthesis of the iridoid glucoside Lamalbid in Lamium barbatum, a plant species in the Lamiaceae, was investigated by administrating (13)C-labeled intermediates of MVA and MEP pathways, respectively. The results demonstrated that [3,4,5-(13)C(3)]1-deoxy-D-xylulose 5-phosphate could be incorporated into Lamalbid, whereas the incorporation of [2-(13)C(1)]mevalonolactone was not observed. Based on the (13)C labeling pattern of Lamalbid and the incorporation data, we deduce that the iridoid glucoside in L. barbatum is biosynthesized through the MEP pathway, whereas the classic MVA pathway is not utilized.

[Iridoid glycosides from Pedicula dicora Franch].[Pubmed:12078153]

Zhongguo Zhong Yao Za Zhi. 1999 Jan;24(1):40-1, 64.

OBJECTIVE: To study the components in the root of Pedicula dicora. METHODS: Column chromatography with silica gel and polyamide was employed for the isolation and purification of ingredients. The structures were elucidated by spectral method. RESULT: Three iridoid glycosides were obtained and elucidated as mussaenoside, shanzhiside methyl ester and Lamalbid. CONCLUSION: All the three compounds were separated from P. dicora for the first time.

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