Products with Inhibitors bioactivity

Cat.No. Product Name
BCN5709 1-Hydroxyrutaecarpine
1. 1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro. 2. 1-Hydroxyrutaecarpine exhibits antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 micrograms/ml. 3. 1-Hydroxyrutaecarpine displays moderate inhibitory activity on those enzymes(Cathepsins B, L and K) at the concentration of 125 ug/ml.
BCN5713 Onitisin
1. Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
BCN5717 Aristolactam BII
1. Aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells by directly inhibiting the production of nitric oxide. 2. Aristolactam BII exhibits antimicrobial and antiinflammatory activity. 3. Aristolactam BII shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom.
BCN5719 Isoastilbin
Isoastilbin has anti-acne and tyrosinase inhibition properties.Isoastilbin, neoastilbin, astilbin and taxifolin have antimicrobial activities, they depress the growth of Streptococcus sobrinus (S. sobrinus) over a concentration range of 9.32-42.7 ug/ml and show GTase inhibitory activity with IC50 values in the range 27.4-57.3 ug/ml.
BCN5721 Decarine
1. Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages. 2. Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.

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