Products with Inhibitors Bioactivity

Explore BioCrick products associated with Inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN5621	Rosenonolactone
1. Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin.
BCN5655	Tectochrysin
Tectochrysin is a promising inhibitor for the reversal of ABCG2-mediated drug transport, it leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of STAT3 phosphorylation.Tectochrysin has antioxidant effect, it also exhibits a significant hepatoprotective activity in hepatic damage induced by CCl4-intoxication in rats.
BCN5656	Tricin
1. Tricin is evaluated as a type of tyrosinase inhibitor. 2. Tricin derivatives conveys allergy and inflammation treatment ability to Z. latifolia. 3. Tricin exerts anti-inflammatory effect via a mechanism involving the TLR4/NF-κB/STAT signaling cascade. 4. Tricin may be beneficial in HSC-targeting therapeutic or chemopreventive applications for hepatic fibrosis. 5. Tricin is a novel compound with potential anti-HCMV activity and that CXCL11 is one of the chemokines involved in HCMV replication.
BCN5664	Evoxine
1. Evoxine is a small molecule that counteracts CO2-Induced immune suppression, it can counteract the CO2-induced transcriptional suppression of antimicrobial peptides in S2* cells. 2. Evoxine and arborinine display moderate antiplasmodial activity against the CQS D10 strain of Plasmodium falciparum, with IC(50) values of 24.5 and 12.3 microM, respectively.
BCN5672	Wedelolactone
Wedelolactone is a potent Î2-arrestin-biased G protein-coupled receptor-35 (GPR35) agonist, GPR35 has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil sodium. Wedelolactone has anti-inflammatory, growth inhibitory, anti-cancer, anti-fibrotic, and pro-apoptotic effects. Wedelolactone stimulates ER genomic and non-genomic signalling pathways; it can significantly inhibit the activation of LX-2 cells, the underlying mechanisms of which included inducing Bcl-2 family involved apoptosis, up-regulating phosphorylated status of ERK and JNK expressions, and inhibiting NF-κB mediated activity.

Inhibitors Bioactivity Products