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Rheum palmatum

Rheum palmatum

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Natural products/compounds from  Rheum palmatum

  1. Cat.No. Product Name CAS Number COA
  2. BCN2914 Isoliquiritin apioside120926-46-7 Instructions
  3. BCN6327 (-)-Epicatechin gallate1257-08-5 Instructions
  4. BCN1003 Sennoside B128-57-4 Instructions
  5. BCN6175 Chrysophanol 8-O-glucoside13241-28-6 Instructions
  6. BCN1688 Catechin154-23-4 Instructions
  7. BCN5392 Rhaponiticin155-58-8 Instructions
  8. BCN8170 Physcion 1-glucoside23451-01-6 Instructions
  9. BCN5947 Rhein478-43-3 Instructions
  10. BCN5565 Aloeemodin481-72-1 Instructions
  11. BCN5567 Chrysophanol481-74-3 Instructions
  12. BCC8146 Chrysophanol 1-glucoside4839-60-5 Instructions
  13. BCN5597 Epicatechin490-46-0 Instructions
  14. BCN5649 Emodin518-82-1 Instructions
  15. BCN5663 Physcion521-61-9 Instructions
  16. BCN1002 Sennoside A81-27-6 Instructions

References

[Anti-inflammatory mechanism of Dahuang Lidan Pian by network pharmacology].[Pubmed: 30111030]


Dahuang Lidan Pian contains Rheum palmatum, Gymnadenia conopsea and Phyllanthus emblica, which has a significant effect in the treatment of alcoholic fatty liver, cholestasis and cholecystitis. The efficacy of the formula in traditional Chinese medicine was clearing heat and promoting diuresis, removing dampness, detoxifying and relieving jaundice. These three herbs are widely used in the traditional Chinese medicine, Mongolian medicine and Tibetan medicine. Therefore, the formula was a representative subject in the researches for ethno-drugs. In this research, computer aided drug design methods were used to predict the action targets of the formula. Protein interaction network (PIN) was then constructed, and molecular complex detection (MCODE) clustering algorithm was used to obtain the modules of the formula, so as to analyze the potential action mechanism. The results showed that Rh. palmatum and P. emblica may have a synergistic protective effect on liver function by acting on analogous targets and pathways. G. conopsea regulated metabolic balance of nutrients to strengthen physical fitness. The research explained the liver-protecting mechanism of Dahuang Lidan Pian based on the PIN analysis on molecular network, which provides an reference for the further study of Dahuang Lidan Pian.