Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2734 | Daphnetin 7-methyl ether |
| Daphnetin 7-methyl ether has anti-inflammatory activity. | |
| BCN2735 | Daphnetin dimethyl ether |
| Daphnetin dimethyl ether is a product from Wikstroemia indica (Linn.) C. A. Mey. | |
| BCN2736 | Oxyimperatorin |
| Oxyimperatorin is a natural product from Angelica dahurica. | |
| BCN2737 | Taccalonolide A |
| Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects. | |
| BCN2738 | Tracheloside |
| Tracheloside significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml). | |
| BCN2739 | Trachelogenin |
| 1. Trachelogenin has antiproliferative effect, the mechanism is related to affect the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway in a concentration-dependent manner. | |
| BCN2740 | Lirioprolioside B |
| Lirioprolioside B is a natural product from Liriope spicata (Thunb.) Lour. | |
| BCN2741 | Onjisaponin B |
| Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease. Onjisaponins may provide safe and potent adjuvants for intranasal inoculation of influenza HA and DPT vaccines. | |
