Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 993 - 1000 of 9359 hot products
| Catalog No. | Product Name |
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| BCC4843 | Salubrinal |
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Cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit <span class='symbol'>α</span> (eIF2<span class='symbol'>α</span>). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC<sub>50</sub> ~ 15 <span class='symbol'>μ</span>M).
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| BCC4849 | SRPIN340 |
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Selective serine arginine protein kinase (SRPK) 1 inhibitor (K<sub>i</sub> = 0.89 <span class='symbol'>μ</span>M). Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Down-regulates expression of VEGF<sub>165</sub> but does not affect VEGF<sub>165b</sub> expression.
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| BCC4850 | STF-118804 |
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NAMPT inhibitor (nicotinamide phosphoribosyltransferase, visfatin, PBEF1); inhibits NAD+ synthesis from nicotinamide. Potently inhibits the viability of multiple B-cell acute lymphoplastic leukemia (B-ALL) cell lines (IC50 < 10 nM); induces apoptosis in MF-411 cells. Induces regression of ALL xenografts and eliminates leukemia stems cells from bone marrow in mice.
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| BCC4860 | Sulfisoxazole |
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A selective ETA endothelin receptor antagonist (IC50 values are 600 and 2200 nM for ETA and ETB receptors respectively).
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| BCC4861 | Sulindac |
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Prodrug. Metabolizes to sulindac sulfide, a cyclooxgenase inhibitor that represses ras signaling, and sulindac sulfone, an antitumor agent, following oral administration in vivo. Widely used anti-inflammatory agent.
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| BCC4862 | Tempol |
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Superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects.
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| BCC4863 | Terbinafine HCl |
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Selective TASK3 activator (pEC50 = 6.2). Exhibits >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2. Also inhibits TWIK1 (pIC50 = 5.69). Also antifungal; inhibits fungal sterol biosynthesis by inhibition of squalene epoxidase.
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| BCC4864 | Thiamet G |
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Potent, selective inhibitor of O-GlcNAcase (Ki = 21 nM for human O-GlcNAcase). Decreases the phosphorylation of tau protein in vivo. Promotes autophagy independently of mTOR pathway and reduces toxic protein species in mouse tauopathy model. Orally bioavailable and blood brain barrier permeable.
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