Home >> Research Area >>Natural Products>>Flavonoids>> 6''-O-Malonylgenistin

6''-O-Malonylgenistin

CAS# 51011-05-3

6''-O-Malonylgenistin

Catalog No. BCN2772----Order now to get a substantial discount!

Product Name & Size Price Stock
6''-O-Malonylgenistin: 5mg $322 In Stock
6''-O-Malonylgenistin: 10mg Please Inquire In Stock
6''-O-Malonylgenistin: 20mg Please Inquire Please Inquire
6''-O-Malonylgenistin: 50mg Please Inquire Please Inquire
6''-O-Malonylgenistin: 100mg Please Inquire Please Inquire
6''-O-Malonylgenistin: 200mg Please Inquire Please Inquire
6''-O-Malonylgenistin: 500mg Please Inquire Please Inquire
6''-O-Malonylgenistin: 1000mg Please Inquire Please Inquire

Quality Control of 6''-O-Malonylgenistin

Number of papers citing our products

Chemical structure

6''-O-Malonylgenistin

3D structure

Chemical Properties of 6''-O-Malonylgenistin

Cas No. 51011-05-3 SDF Download SDF
PubChem ID 15934091 Appearance Powder
Formula C24H22O13 M.Wt 518.42
Type of Compound Flavonoids Storage Desiccate at -20°C
Synonyms Malonylgenistin; Genistin malonate
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-oxo-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-3-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methoxy]propanoic acid
SMILES C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)OC4C(C(C(C(O4)COC(=O)CC(=O)O)O)O)O)O
Standard InChIKey FRAUJUKWSKMNJY-RSEYPYQYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 6''-O-Malonylgenistin

The seeds of Glycine max (L.) Merr

Biological Activity of 6''-O-Malonylgenistin

Description6''-O-Malonylgenistin possesses a hepatoprotective activity.
In vitro

Isoflavone content and its potential contribution to the antihypertensive activity in soybean Angiotensin I converting enzyme inhibitory peptides.[Pubmed: 18921974]

J Agric Food Chem. 2008 Nov 12;56(21):9899-904.

A soybean angiotensin I converting enzyme (ACE) inhibitory peptide fraction was reported to have antihypertensive activity in a rat study. The purpose of the present study was to examine if the presence of isoflavones in the soybean ACE inhibitory peptide fraction may contribute to the blood-pressure-lowering property.
METHODS AND RESULTS:
The isoflavone concentration in soybean samples was analyzed on a C 18 reverse-phase column using a two-step gradient solvent system. Producing soybean hydrolysate led to a nearly 40% loss of isoflavones compared with the original soybean flour, but the isoflavone composition did not change and the dominant isoflavone chemicals remained as 6''-O-Malonylgenistin and 6''-O-malonyldaidzin. Ion exchange chromatography affected significantly both the content and the composition of the isoflavones. The dominant isoflavones in the ion-exchanged fraction were aglycones and nonacylated isoflavones, accounting for 95.8% of the total amount of 987.7 microg/g. It was calculated that the isoflavone content in the soybean ACE inhibitory peptide fraction was 25 times less than the minimal effective isoflavone dose reported. In vitro study also showed that adding isoflavones into both soybean flour hydrolysate and soybean ACE inhibitory peptide samples to a concentration of as high as 31.5% (w/w) did not affect ACE inhibitory activity (IC 50 values).
CONCLUSIONS:
The findings along with previously published results indicated that the contribution of isoflavones in soybean ACE inhibitory peptide fraction to the blood-pressure-lowering property in a short-term feeding study might be negligible.

Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim.[Pubmed: 18671403]

J Agric Food Chem. 2008 Aug 27;56(16):7023-31.

Isoflavonoids, an interesting and restricted group of secondary metabolites of legumes, exhibit estrogenic, antiangiogenic, and anticancer activities and are now popular as dietary supplements. Plant cell cultures that possess an increased ability to synthesize these metabolites were examined.
METHODS AND RESULTS:
During the investigation, cell cultures of the Far Eastern relict tree Maackia amurensis (Leguminosae) were established. A selection of seed-derived cell aggregates yielded the callus line designated A-18. This culture produces 20 isoflavonoids, namely, the isoflavones genistein, daidzein, formononetin, calycosin, derrone, and pseudobaptigenin and their glycosylated conjugates genistin, 6''-O-Malonylgenistin, ononin, 6''-O-malonylononin, daidzin, 3'-methoxydaidzin, 4'-O-beta-D-glucopyranosyldaidzin, 4'-O-beta-D-glucopyranosylgenistin, and 7-O-beta-D-glucopyranosylcalycosin; the pterocarpans maackiain and medicarpin and their glycosylated conjugates 6'-O-malonyl-3-O-beta-D-glucopyranosylmaackiain and 6'-O-malonyl-3-O-beta-D-glucopyranosylmedicarpin; and the new pterocarpan glucoside 6'-O-malonyl-3-O-beta-D-glucopyranosyl-6,6a-dehydromaackiain.
CONCLUSIONS:
These isoflavonoids, possessing a hepatoprotective activity, were stably produced by the A-18 calli for prolonged periods of observation.

6''-O-Malonylgenistin Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

6''-O-Malonylgenistin Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 6''-O-Malonylgenistin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9289 mL 9.6447 mL 19.2894 mL 38.5788 mL 48.2234 mL
5 mM 0.3858 mL 1.9289 mL 3.8579 mL 7.7158 mL 9.6447 mL
10 mM 0.1929 mL 0.9645 mL 1.9289 mL 3.8579 mL 4.8223 mL
50 mM 0.0386 mL 0.1929 mL 0.3858 mL 0.7716 mL 0.9645 mL
100 mM 0.0193 mL 0.0964 mL 0.1929 mL 0.3858 mL 0.4822 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University

Background on 6''-O-Malonylgenistin

6''-O-Malonylgenistin(Malonylgenistin) is an isoflavone derivative.

References:
[1]. Fedoreyev SA, et al. Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim. J Agric Food Chem. 2008 Aug 27;56(16):7023-31. [2]. Wu J, et al. Isoflavone content and its potential contribution to the antihypertensive activity in soybean Angiotensin I converting enzyme inhibitory peptides. J Agric Food Chem. 2008 Nov 12;56(21):9899-904.

Featured Products
New Products
 

References on 6''-O-Malonylgenistin

Isoflavone content and its potential contribution to the antihypertensive activity in soybean Angiotensin I converting enzyme inhibitory peptides.[Pubmed:18921974]

J Agric Food Chem. 2008 Nov 12;56(21):9899-904.

A soybean angiotensin I converting enzyme (ACE) inhibitory peptide fraction was reported to have antihypertensive activity in a rat study. The purpose of the present study was to examine if the presence of isoflavones in the soybean ACE inhibitory peptide fraction may contribute to the blood-pressure-lowering property. The isoflavone concentration in soybean samples was analyzed on a C 18 reverse-phase column using a two-step gradient solvent system. Producing soybean hydrolysate led to a nearly 40% loss of isoflavones compared with the original soybean flour, but the isoflavone composition did not change and the dominant isoflavone chemicals remained as 6''-O-malonylgenistin and 6''-O-malonyldaidzin. Ion exchange chromatography affected significantly both the content and the composition of the isoflavones. The dominant isoflavones in the ion-exchanged fraction were aglycones and nonacylated isoflavones, accounting for 95.8% of the total amount of 987.7 microg/g. It was calculated that the isoflavone content in the soybean ACE inhibitory peptide fraction was 25 times less than the minimal effective isoflavone dose reported. In vitro study also showed that adding isoflavones into both soybean flour hydrolysate and soybean ACE inhibitory peptide samples to a concentration of as high as 31.5% (w/w) did not affect ACE inhibitory activity (IC 50 values). The findings along with previously published results indicated that the contribution of isoflavones in soybean ACE inhibitory peptide fraction to the blood-pressure-lowering property in a short-term feeding study might be negligible.

Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim.[Pubmed:18671403]

J Agric Food Chem. 2008 Aug 27;56(16):7023-31.

Isoflavonoids, an interesting and restricted group of secondary metabolites of legumes, exhibit estrogenic, antiangiogenic, and anticancer activities and are now popular as dietary supplements. Plant cell cultures that possess an increased ability to synthesize these metabolites were examined. During the investigation, cell cultures of the Far Eastern relict tree Maackia amurensis (Leguminosae) were established. A selection of seed-derived cell aggregates yielded the callus line designated A-18. This culture produces 20 isoflavonoids, namely, the isoflavones genistein, daidzein, formononetin, calycosin, derrone, and pseudobaptigenin and their glycosylated conjugates genistin, 6''-O-malonylgenistin, ononin, 6''-O-malonylononin, daidzin, 3'-methoxydaidzin, 4'-O-beta-D-glucopyranosyldaidzin, 4'-O-beta-D-glucopyranosylgenistin, and 7-O-beta-D-glucopyranosylcalycosin; the pterocarpans maackiain and medicarpin and their glycosylated conjugates 6'-O-malonyl-3-O-beta-D-glucopyranosylmaackiain and 6'-O-malonyl-3-O-beta-D-glucopyranosylmedicarpin; and the new pterocarpan glucoside 6'-O-malonyl-3-O-beta-D-glucopyranosyl-6,6a-dehydromaackiain. These isoflavonoids, possessing a hepatoprotective activity, were stably produced by the A-18 calli for prolonged periods of observation.

Description

6''-O-Malonylgenistin(Malonylgenistin) is an isoflavone derivative.

Keywords:

6''-O-Malonylgenistin,51011-05-3,Malonylgenistin; Genistin malonate,Natural Products, buy 6''-O-Malonylgenistin , 6''-O-Malonylgenistin supplier , purchase 6''-O-Malonylgenistin , 6''-O-Malonylgenistin cost , 6''-O-Malonylgenistin manufacturer , order 6''-O-Malonylgenistin , high purity 6''-O-Malonylgenistin

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: