Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1025 - 1032 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC4930 | Primidone |
|
Anticonvulsant.
|
|
| BCC4934 | Reboxetine mesylate |
|
Potent and selective inhibitor of noradrenalin uptake (K<sub>i</sub> values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over <span class='symbol'>α</span>-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.
|
|
| BCC4935 | Ribavirin |
|
Antiviral guanosine ribonucleoside analog; misincorporated into mRNA by viral-dependent RNA polymerases. Binds to and redistributes mammalian eIF4E from the nucleus to the cytoplasm (K<sub>i</sub> ~ 0.3 <span class='symbol'>μ</span>M for the active metabolite, ribavirin triphosphate). Represses colony formation of primary AML-M5 progenitor cells (IC<sub>50</sub> ~ 1 <span class='symbol'>μ</span>M); reduces disease severity in acute myeloid leukemia (AML). Orally available.
|
|
| BCC4939 | Ropinirole HCl |
|
Selective D2-like receptor agonist (D3 > D2 > D4). Causes biphasic spontaneous locomotor activity and contralateral circling in 6-OHDA-lesioned mice. Displays antiParkinsonian activity.
|
|
| BCC4945 | Ursodiol |
|
Ursodeoxycholic acid is a potent inhibitor of apoptosis, it prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation. Ursodeoxycholic acid can ameliorate experimental ileitis counteracting intestinal barrier dysfunction and oxidative stress, it as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis.
|
|
| BCC4949 | Calcifediol |
|
Prohormone of calcitriol. Major circulating form of vitamin D. Suppresses PTH synthesis and secretion in bovine parathyroid cells (ED50 = 2 nM).
|
|
| BCC4950 | Calcitriol |
|
Active metabolite of vitamin D<sub>3</sub> that activates the vitamin D receptor (VDR). Displays calcemic actions; stimulates intestinal and renal Ca<sup>2+</sup> absorption and regulates bone Ca<sup>2+</sup> turnover. Exhibits antitumor activity; inhibits <em>in vivo</em> and <em>in vitro</em> cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.
|
|
| BCC4952 | Tacrolimus (FK506) |
|
1. Tacrolimus versus ciclosporin are primary immunosuppression for kidney transplant recipients.
|
|