Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN1520 | Quercetin 3-O-glucoside-7-O-rhamnoside |
| 1. Quercetin 3-O-glucoside-7-O-rhamnoside at 30 mg/kg i.p. can decrease the ambulatory locomotor activity and increase the sodium thiopental-induced time of loss of the righting reflex suggesting a clear depressant action. | |
| BCN1528 | Isorhamnetin 3-glucoside-7-rhamnoside |
| 1. An anti-oxidative composition containing isorhamnetin-3-glucoside-7-rhamnoside (IGR)isolated from Hippophae rhamnoides L. is provided to ensure antioxidative, antibacterial, and anti-cancer effect; a cosmetic composition for preventing or treating aging contains IGR compound as an active ingredient; a health food composition for antioxiaiton contains IGR as an active ingredient; a pharmaceutical composition for antibacterial and anticancer contains IGR as an active ingredient. | |
| BCN8456 | Flavokawain C |
| Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 uM. Flavokawain C has anti-tumor activity, it inhibited cell cycle and promoted apoptosis, associated with endoplasmic reticulum stress and regulation of MAPKs and Akt signaling pathways in HCT 116 human colon carcinoma cells.Flavokawain B and flavokawain C are melanogenesis inhibitors, they inhibit melanogenesis with IC50 values of 7.7uM and 6.9 uM, respectively. Flavokawain C inhibits cell cycle and promotes apoptosis, associated with endoplasmic reticulum stress and regulation of MAPKs and Akt signaling pathways in HCT 116 human colon carcinoma cells. | |
| BCN2867 | Galanthaminone |
| 1. Galanthaminone (Narwedin) is a competitive and reversible cholinesterase (AChE) inhibitor; is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments. | |
| BCN2868 | Galantamine |
| 1. Galantamine is an acetylcholinesterase inhibitor, can reduce brain damage induced by hypoxia-ischemia 2. Galantamine may be a candidate drug for treating relapses of METH-seeking behavior. | |
| BCN2869 | Galantamine hydrobromide |
| Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. | |
| BCN2871 | Ganoderic acid M |
| 1. Ganoderic acid Me and/or ganoderic acid T have obvious action for inhibiting human tumor cell growth or proliferation, at the same time its toxicity for normal cells is low. | |
| BCN2879 | Dihydrodaidzin |
| 1. Dihydrodaidzin shows cytotoxic activities against human stomach carcinoma (Hs 740.T, Hs 756 T), breast adenocarcinoma (Hs 578 T, Hs 742.T), and prostate carcinoma (DU 145, LNCaP-FGC) cell lines. | |
