Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN2900 3'-Methoxypuerarin
1. 3'-Methoxypuerarin (3'-MOP) can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 2. 3'-Methoxypuerarin has antioxidant activities, it shows ONOO(-) scavenging activity and weak NO· and O(2)(-) scavenging activities.
BCN6387 Trillenoside A
1. Saponin V (300,150,75 mg·kg-1) can significantly decrease the times of cough, saponin V 300 mg/kg can remarkably increase cough latent period, saponin V 5 g/L remarkably antagonized contraction of isolated ileum, saponin V 2.5 and 1.25 g/L antagonized trachea spasm in guinea pig induced by histamine; saponin V exhibits significant antitussive, expectorant and antispasmodic effects. 2. Chikusetsu saponin V can attenuate H2O2-induced oxidative stress in human neuroblastoma SH-SY5Y cells through Sirt1/PGC-1α/Mn-SOD signaling pathways, suggests that chikusetsu saponin V exhibits neuroprotective effects.
BCN2902 Aristolochic acid D
1. Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxic and carcinogenic aristolochic acids .
BCN2904 DL-alpha-Tocopherylacetate
1. Dl-alpha-Tocopherylacetate shows anti-inflammatory and analgesic activity, it acts synergistically with aspirin towards reducing inflammation and pain as well as the former reduced the gastric ulcerogenic potential of the latter. 2. Dl-alpha-Tocopherylacetate induces hypocoagulability and platelet hypoaggregability in rats. 3. Dl-alpha-tocopheryl acetate is a dietary supplement.
BCN6385 Platycoside E
1. Platycoside E can significantly promote the production of the sera ovalbumin (OVA)-specific IgG2a and IgG2b antibody in the OVA-immunized mice .
BCN2905 Clerosterol
1. Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. 2. Clerosterol exerts its cytotoxic effect in A2058 human melanoma cells by caspases-dependent apoptosis.
BCN1448 Oxyresveratrol 2-O-beta-D-glucopyranoside
Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
BCN1531 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid
1. 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid shows anti-inflammatory activity, it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells.