Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1081 - 1088 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5049 | IEM 1754 dihydrobroMide |
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Voltage-dependent open-channel blocker of AMPA receptors. Selective between subtypes; blocks GluR2 subunit-lacking (Ca<sup>2+</sup>-permeable) receptors more potently than GluR2-containing receptors. Also potently blocks NMDA receptor channels. Less sensitive than IEM at a holding potential between -40 and -80mV.
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| BCC5051 | Lamotrigine |
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Anticonvulsant. Inhibits glutamate release, possibly through inhibition of Na<sup>+</sup>, K<sup>+</sup> and Ca<sup>2+</sup> currents. Also blocks heterologously expressed and native <span class='symbol'>α</span>4<span class='symbol'>β</span>2 nAChRs with a similar affinity to Na<sup>+</sup> channels. Water-soluble salt available lamotrigine isethionate.
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| BCC5052 | LY310762 |
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5-HT<sub>1D</sub>-preferring receptor antagonist (EC<sub>50 </sub>= 31 nM). Displays no activity on 5-HT transport.
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| BCC5056 | SB269970 HCl |
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Potent and selective 5-HT7 receptor antagonist (pKi values are 8.9, 7.2 and 6.0 for 5-HT7A, 5-HT5A and 5-HT1B and < 6.0 for 5-HT1A, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT4 and 5-HT6 receptors respectively). Brain penetrant in vivo.
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| BCC5059 | Sertraline HCl |
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Potent, orally active selective serotonin re-uptake inhibitor (SSRI); antidepressant.
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| BCC5060 | VUF 10166 |
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High affinity 5-HT<sub>3</sub> receptor antagonist (IC<sub>50</sub> values are 0.04 and 22 nM for human 5HT<sub>3A</sub> and 5-HT<sub>3AB</sub> receptors respectively). Exhibits partial agonist activity at 5-HT<sub>3A</sub> receptors at higher concentrations (EC<sub>50</sub> = 5.2 <span class='symbol'>μ</span>M). Also histamine H<sub>4</sub> receptor antagonist (pK<sub>i</sub> = 6.64 in HEK cells).
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| BCC5062 | Zolmitriptan |
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Potent 5-HT1B/1D/1F agonist (Ki values are 0.63, 5.01 and 63.09 nM for h5-HT1D, h5-HT1B and h5-HT1F receptors respectively). Inhibits trigeminal nerve stimulation-mediated neurogenic plasma protein extravasation in guinea pigs; blocks long excitatory postsynaptic potentials (EPSPs) in a rat model of spinal cord injury.
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| BCC5063 | BMY 7378 |
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5-HT<sub>1A</sub> partial agonist and high affinity <span class='symbol'>α</span><sub>1D</sub> adrenoceptor antagonist (K<sub>i</sub> values are 2, 800 and 600 nM at cloned rat <span class='symbol'>α</span><sub>1D</sub>, rat <span class='symbol'>α</span><sub>1A</sub> and hamster <span class='symbol'>α</span><sub>1B</sub> receptors respectively). Also available as part of the <span class='symbol'>α</span><sub>1</sub>-Adrenoceptor.
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