Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 1121 - 1128 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCC5165 Sotalol hydrochloride
A relatively potent pure <span class='symbol'>&beta;</span> adrenergic antagonist, unique in possessing additional class III antiarrhythmic activity. Also available as part of the Mixed Adrenergic.
BCC5178 GSK269962A
Potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). Displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. Induces vasorelaxation in preconstricted rat aorta (IC50 = 35 nM); lowers blood pressure in a rat model of hypertension.
BCC5182 AMD 3465 hexahydrobromide
Potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100. Inhibits SDF-1<span class='symbol'>&#945;</span>-ligand binding (K<sub>i</sub> = 41.7 nM). Potently inhibits HIV cell entry <em>in vitro</em>; causes leukocytosis and mobilizes haematopoietic stem cells <em>in vivo</em>.
BCC5186 Miglustat hydrochloride
Orally active <span class='symbol'>&#945;</span>-glucosidase I and II and ceramide-specific glycosyltransferase inhibitor. Rescues trafficking-deficient F508del-CFTR in human airway epithelial cells via inhibition of ER <span class='symbol'>&#945;</span>-glucosidases I and II. Also has broad spectrum antiviral activity.
BCC5189 Travoprost
FP prostaglandin receptor agonist. Exhibits submicromolar affinity for DP, EP, IP and TP receptors. Stimulates intracellular Ca2+ mobilization. Ocular hypotensive agent.
BCC5196 R-(-)-Deprenyl hydrochloride
Selective inhibitor of monoamine oxidase B (MAO-B).
BCC5197 Zaleplon
Non-benzodiazepine agent that acts as an agonist at the benzodiazepine site. Displays hypnotic, anxiolytic, myorelaxant and anticonvulsant activity.
BCC5199 U-73122
Phospholipase C inhibitor. Inhibits agonist-induced platelet aggregation with IC<sub>50</sub> values of 1-5 <span class='symbol'>&mu;</span>M. Potently inhibits human polymorphonuclear neutrophil adhesion on biological surfaces (IC<sub>50</sub> &lt; 50 nM) and exhibits antinociceptive activity <em>in vivo</em>. Also activates TRPM4 and inhibits TRPM3 channels. Negative control U 73343 also available.