Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN1368 | Methylnissolin |
| Methylnissolin is a natural product from A. membranaceus. | |
| BCN1428 | Isomucronulatol |
| 1. Isoliquiritigenin and liquiritigenin exhibit significant inhibitory effects on LPS-induced IL-6 and IL-12 p40 production, with IC 50 values ranging from 2.7 to 6.102uM, isoliquiritigenin also shows a moderate inhibitory effect on LPS-stimulated production of TNF-α with an IC 50 value of 20.102 uM, they have potential anti-inflammatory effects. 2. Isomucronulatol exhibits noticeable ABTS+ scavenging activity, it exhibits moderate inhibition against butyrylcholinesterase. | |
| BCN1511 | Rubrosterone |
| 1. Rubrosterone is an insect-molting C19-steroid. | |
| BCN1486 | Leptomerine |
| 1. Leptomerine (IC₅₀ = 2.5 mM) shows potent anticholinesterasic activity. | |
| BCN1317 | N-Benzyloleamide |
| 1. N-benzyloleamide has pharmaceutical property against exercise-induced fatigue, and this effect can be explained by the modulated energy metabolism and improved antioxidant status. | |
| BCN6383 | 2-Cinnamoyl-1-galloylglucose |
| 1. N-(3-methoxybenzyl)palmitamide is a promising inhibitor of fatty acid amide hydrolase (FAAH) and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders. 2. N-(3-Methoxybenzyl)palmitamide can counteract the toxicity produced by Aβ (25-35). | |
| BCN6475 | Okanin |
| 1. Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect. 2. Okanin shows significant protective effects against tacrine-induced cytotoxicity in human liver-derived Hep G2 cells with the EC50 value of 29.8±1.1 uM. 3. Okanin can inhibit nitric oxide production and inducible nitric oxide synthase expression via nuclear factor-erythroid 2-related factor 2-dependent heme oxygenase-1 expression in lipopolysaccharide-activated macrophages. 4. Okanin attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways, suggests that okanin may have potential as a nutritional preventive strategy for neurodegenerative disorders. | |
| BCN6476 | Isookanin |
| 1. Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity, with the IC50 value of 7.9 ± 0.53 uM. 2. Isookanin is a potent inhibitor of α-amylase (IC₅₀=0.447 mg/ml). | |
