Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1169 - 1176 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5338 | 4E1RCat |
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Inhibitor of protein translation; blocks eIF4E:eIF4G and eIF4E:4E-BP1 interaction. Prevents assembly of the eIF4F complex and inhibits cap-dependent translation (IC<sub>50</sub> ~4 <span class='symbol'>μ</span>M). Exhibits chemosensitizing properties.
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| BCC5340 | ISRIB (trans-isomer) |
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Integrated stress response (ISR) inhibitor; reverses the effects of eIF2<span class='symbol'>α</span> phosphorylation (IC<sub>50</sub> = 5 nM) and restores cell translation capacity. Acts downstream of PERK, targeting interactions between eIF2<span class='symbol'>α</span> kinases and elF2B. Blocks ATF4 production without altering the IRE1 or ATF6 responses <em>in vitro</em>. Displays memory enhancement in hippocampus-dependent spatial and fear-associated learning in rodents. Brain penetrant.
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| BCC5341 | FH1(BRD-K4477) |
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Enhances differentiation of induced pluripotent stem cells (iPSCs) to hepatocytes; also promotes the maturation of iPSC-derived hepatocytes.
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| BCC5343 | MSDC-0160 |
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Insulin sensitizer; enhances insulin sensitivity and lowers blood-glucose levels in diabetic mouse models. Inhibits mitochondria pyruvate carriers; increases mitochondrial respiration rates, leading to a reduction in expression of lipogenic enzymes. Suppresses gluconeogenesis and lipogenesis in primary hepatocytes. Exhibits low binding affinity and activity at PPAR<span class='symbol'>γ</span> (EC<sub>50</sub> = 23.7 <span class='symbol'>μ</span>M).
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| BCC5344 | LB42708 |
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Selective inhibitor of farnesyltransferase (FTase). Blocks farnesylation of H-Ras, N-Ras and K-Ras4B (IC50 values are 0.8, 1.2 and 2.0 nM respectively). Displays >50,000-fold selectivity for FTase over geranylgeranyltransferase (GGTase) I. Inhibits VEGF-induced Ras activation; suppresses angiogenesis in vivo and in vitro (IC50 = 75 nM). Orally active.
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| BCC5350 | Midostaurin (PKC412) |
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Broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms (<span class='symbol'>α</span>, <span class='symbol'>β</span>, <span class='symbol'>γ</span>), PDFR<span class='symbol'>β</span>, VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity.
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| BCC5355 | Roquinimex |
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Immunomodulator with stimulatory and antitumor properties. Inhibits in vivo apoptosis of T cells and inhibits angiogenesis in rats in vivo.
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| BCC5365 | β-Estradiol - d3 |
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Deuterated β-estradiol.
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