Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1185 - 1192 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5391 | Dobutamine hydrochloride |
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<span class='symbol'>β</span><sub>1</sub>- and <span class='symbol'>β</span><sub>2</sub>-adrenoceptor agonist with some action at the <span class='symbol'>α</span><sub>1</sub>-adrenoceptor.
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| BCC5393 | GW311616 |
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Potent and selective inhibitor of human leukocyte elastase (HLE) (IC50 = 22 nM); displays > 4500-fold selectivity over other human serine proteases. Orally active in vivo.
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| BCC5401 | iCRT 14 |
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Potent inhibitor of <span class='symbol'>β</span>-catenin-responsive transcription (CRT) (IC<sub>50</sub> = 40.3 nM in assays of Wnt pathway activity). Thought to directly influence the interaction between <span class='symbol'>β</span>-catenin and TCF4. Induces marked G<sub>0</sub>/G<sub>1</sub> cell cycle arrest in HCT-116 and HT29 cell lines.
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| BCC5403 | HLM006474 |
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E2F transcription factor inhibitor; inhibits E2F DNA binding activity. Inhibits E2F4 DNA binding and reduces E2F4 protein levels in A375 melanoma cells. Induces apoptosis of A375 and MDA-MB-231 breast cancer cells. Inhibits A375 proliferation and invasion in a three dimensional skin model of A375 invasion. Also attenuates human embryonic stem cell proliferation.
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| BCC5422 | Eltoprazine hydrochloride |
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5-HT1 and 5-HT2C receptor partial agonist (Ki values are 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo.
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| BCC5424 | VU 0240551 |
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Inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2-overexpressing cells). Exhibits selectivity over the Na-K-2Cl cotransporter, NKCCl. Also inhibits hERG and L-type Ca2+ channels.
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| BCC5425 | BTS |
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Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.
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| BCC5426 | AK-7 |
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Selective SIRT2 inhibitor (IC<sub>50</sub> = 15.5 <span class='symbol'>μ</span>M); displays no effect on SIRT1 or SIRT3. Decreases neuronal cholesterol levels; improves motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Brain penetrant.
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