Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7831 Epimagnolin A
Epimagnolin A affects the transport activity of ABCB1(a major transmembrane efflux pump belonging to the ABC transporter superfamily), it also exhibits growth inhibitory activity against larvae of Drosophila melanogaster.
BCN7832 3-O-beta-D-Glucopyranosylplatycodigenin
1. 3-O-beta-D-Glucopyranosylplatycodigenin may have in vitro anti-proliferative activity against the HSC-T6 cell line.
BCN7833 Coumarin VI
Coumarin VI is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.
BCN7835 Genistein 7,4'-di-O-beta-D-glucopyranoside
1. Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.
BCN6432 D-(+)-Fucose
1. D-(+)-Fucose is a hexose deoxy sugar found on N-linked glycans that appears on the cell surface of mammalian and plant cells.
BCN2975 Jervine
Jervine exhibits cytotoxic activity against human tumor cell lines A549, PANC-1, SW1990 and NCI-H249, it induces COX-2 overexpression in human erythroleukemia cells. Jervine exhibits potent toxic effects against Colorado potato beetle.
BCN7841 Gymnemagenin
1. Gymnemagenin, one of the key constituents of G. sylvestre against 15 proteins having key role in carbohydrate metabolism, it can be considered further for development into a potent anti-diabetic drug. 2. Gymnemagenin has antihyperglycemic activity. 3. Gymnemagenin is a potent and selective antagonist for the β isoform of LXR.
BCN7845 Isoscoparin
1. Isoscoparin has antioxidant activity. 2 . Isoscoparin has potential anti-adipogenic effects, it may be a potential therapeutic agent for the prevention and treatment of obesity. 3. Isoscoparin can significantly inhibit the production of both NO and TNF-α at a concentration of 2.0 uM.