Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8233 | 19-Oxocinobufotalin |
| 1. 19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro. | |
| BCN8234 | Pseudobufarenogin |
| 1. Pseudobufarenogin(ψ-bufarenogin), a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling. 2. ψ-Bufarenogin shows inhibition of human kidney Na(+)/K(+)-ATPase activity. | |
| BCN8235 | (-)-Anonaine |
| 1. (-)-Anonaine has some anticancer activity, it induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells. 2. (-)-Anonaine may be considered a potent compound for chemotherapy against cervical cancer or a health food supplement for cancer chemoprevention. 3. (-)-Anonaine has vasorelaxant effect. 4. (-)-Anonaine induces DNA damage and inhibits growth and migration of human lung carcinoma h1299 cells. | |
| BCN8236 | Roemerine |
| 1. Roemerine possesses antibacterial activity, it improves the survival rate of septicemic BALB/c mice by increasing the cell membrane permeability of Staphylococcus aureus. 2. Roemerine is a potential active xanthine oxidase(XOD) inhibitor, XOD is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to treat gout. 3. Roemerine has some anti-prostate cancer effect and alleviates adverse reactions in paclitaxel combination administration. 4. Roemerine shows significant anti-plasmodial activities with IC(50) ranged from 1.2 μM to 52.3 uM. | |
| BCN8238 | Hellebrigenol |
| 1. Hellebrigenol shows cytotoxicity against HepG2 cells. | |
| BCN8239 | Colutehydroquinone |
| 1. Colutehydroquinone and colutequinone are antifungal isoflavonoids from Colutea arborescens. | |
| BCN8240 | Odoriflavene |
| 1. Odoriflavene has antioxidant activity, and it also shows inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation. 2. Odoriflavene shows cytotoxic activity against a SH-SY5Y cell line in vitro. | |
| BCN8244 | Eclalbasaponin I |
| 1. Eclalbasaponin I has anti-oxidative effect, it reduces oxidative stress-induced neural cell death by autophagy activation. 2. Eclalbasaponin I shows antitumor activity, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 with the IC(50) value of 111.1703 ug/ml. | |
