Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1249 - 1256 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5623 | Garcinol |
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Inhibitor of PCAF and p300 histone acetyltransferase (HAT) activity (IC<sub>50</sub> values are 5 and 7 <span class='symbol'>μ</span>M, respectively). Promotes expansion of human HSCs <em>ex vivo</em>. Causes reversal of EMT and inhibits <span class='symbol'>β</span>-catenin in breast cancer cell lines MDA-MB-231 and BT-549.
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| BCC5624 | A 366 |
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Potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM). Exhibits >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. Decreases levels of lysine 9 dimethylation on histone H3 (H3K9Me2) in PC3 cells.
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| BCC5625 | UNC 2400 |
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Negative control of UNC 1999. Exhibits 1000-fold lower potency than active analog (IC<sub>50</sub> values are 62 and >200 <span class='symbol'>μ</span>M for EZH1 and EZH2, respectively).
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| BCC5626 | WDR5 0103 |
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WD repeat-containing protein 5 (WDR5) antagonist (Kd = 450 nM). Disrupts WDR5 interaction with MLL and inhibits MLL core complex methyltransferase activity in vitro. Has no effect on a panel of seven other methyltransferases, including SETD7.
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| BCC5638 | KN-93 Phosphate |
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CaM kinase II inhibitor; water soluble version of KN 93.
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| BCC5643 | Octreotide acetate |
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Peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 - 1140 (sst1), 0.4 - 2.1 (sst2), 4.4 - 34.5 (sst3), > 1000 (sst4), and 5.6 - 32 (sst5).
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| BCC5644 | Pentamidine isethionate |
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Antimicrobial. Neuroprotective; inhibits constitutive nitric oxide synthase in the brain and acts as a NMDA glutamate receptor antagonist.
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| BCC5646 | Topotecan |
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TLyp-1-functionalized topotecan-loaded niosomes could significantly improve anti-glioma treatment. Preparation of topotecan into a temperature-sensitive phase-change hydrogel achieves a long-term sustained antitumor effect on Rb cells, and may be a useful strategy for the treatment of intraocular Rb.
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