Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7994 | Uralenol |
| 1. Uralenol significantly shows the inhibitory activities against the PTP1B enzyme. 2. Uralenol shows inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate（IC50 =49.5 uM). 3. Uralenol shows potent anti-proliferation effects on ER-positive breast cancer MCF-7 cells in vitro. | |
| BCN7990 | Caulophine |
| 1. Caulophine has the ability to protect cardiomyocytes from oxidative and ischemic injury through an antioxidative mechanism. | |
| BCN7988 | Baptifoline |
| 1. Baptifoline has cytotoxic activity. | |
| BCN7987 | Gossypin |
| 1. Gossypin exerts potent radical scavenging activity generated from 1,1-diphenyl-2-picrylhydrazyl. 2. Gossypin exerts neuroprotective effects in the cultured cortical cells by inhibiting oxidative stress- and Abeta-induced toxicity, and that the antioxidant properties of gossypin may contribute to its neuroprotective actions. 3. Gossypin inhibits the NF-kappaB activation pathway, which may explain its role in the suppression of inflammation, carcinogenesis, and angiogenesis. 4. Gossypin has anticonvulsant activity. 5. Gossypin is a new hypocholesterolemic agent that up-regulates LDLR expression independent of SREBP-2 but is dependent on ERK activation. 6. Gossypin has antiinflammatory and antinociceptive activities. 7. Gossypin has anti-allergic activity, it i can nhibit mast cell-derived allergic reactions. 8. Gossypin has antidiabetic activity in streptozotocin-induced experimental diabetes in rats. 9. Gossypin has cytotoxic and antibacterial activities. 10. Gossypin has ameliorative effect against gentamicin-induced nephrotoxicity in rats. 11. Gossypin shows inhibitory effects on RANKL-induced osteoclast differentiation and bone resorption in murine macrophages (LB364). | |
| BCN7986 | Isoshinanolone |
| 1. Isoshinanolone shows excellent toxicity with LC(50) values of 1.26 microg/mL. 2. trans-Isoshinanolone shows cytotoxicity against MDA-MB-231 breast cancer cells. | |
| BCN7985 | Droserone |
| 1. Droserone inhibits in vitro measles virus infection. 2. Droserone exerts an antifungal effect on a wide range of plant and human fungal pathogens. | |
| BCN7979 | 9-Hydroxythymol |
| 1. 9-Hydroxythymol has antibacterial activity. | |
| BCN7978 | Arnicolide C |
| 1. Arnicolide C exhibits significant antiallergy activity. | |
