Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1297 - 1304 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5694 | RS 39604 hydrochloride |
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A potent and selective 5-HT<sub>4</sub> antagonist, with a pK<sub>i</sub> of 9.1 at 5-HT<sub>4</sub> receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT<sub>1A, 2C, 3</sub> and D<sub>1</sub>, D<sub>2</sub>, M<sub>1</sub>, M<sub>2</sub>, AT<sub>1,</sub> B<sub>1</sub> and <span class='symbol'>α</span><sub>1C</sub> receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for <em>in vivo</em> studies.
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| BCC5695 | L-745,870 trihydrochloride |
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A highly potent and selective D4 dopamine receptor antagonist; L-745,870 has Ki values of 0.51, 2300 and 960 nM for D4, D3 and D2 subtypes respectively and > 1000-fold selectivity over 5-HT2, D1 and D5 receptors.
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| BCC5696 | L-741,742 hydrochloride |
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A potent and highly selective D4 dopamine receptor antagonist, with Ki values of > 1700, 770 and 3.5 nM at cloned human D2, D3 and D4 receptors.
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| BCC5697 | Endomorphin-2 |
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Endogenous peptide with extremely high affinity and selectivity for <span class='symbol'>μ</span>-opioid receptors (with K<sub>i</sub> values of 0.69, 9233 and 5240 nM for <span class='symbol'>μ</span>, <span class='symbol'>δ</span> and <span class='symbol'>κ</span> respectively).
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| BCC5698 | Methysergide maleate |
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Mixed 5-HT<sub>1</sub>/5-HT<sub>2</sub> receptor antagonist.
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| BCC5699 | ω-Conotoxin MVIIC |
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Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.
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| BCC5700 | ω-Conotoxin GVIA |
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Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC<sub>50</sub> = 0.15 nM). Reduces (<em>RS</em>)-3,5-DHPG-induced long term depression <em>in vivo</em>.
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| BCC5701 | [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 |
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Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo. Selective, competitive antagonism at the nociceptin receptor has also been reported (pA2 = 7.02 and 6.75 in the guinea pig ileum and mouse vas deferens respectively).
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