Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1353 - 1360 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5750 | [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide |
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Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
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| BCC5751 | SB 200646 hydrochloride |
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5-HT2C/2B receptor antagonist, selective over 5-HT1A. Affinities are 7.4 (pA2), 6.9 (pKi) and 5.2 (pKi) for 5-HT2B, 2C and 2A respectively. Orally active in vivo.
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| BCC5752 | SB 204070 |
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Potent and selective 5-HT4 receptor antagonist (pIC50 = 10.1). Displays >5000-fold selectivity for 5-HT4 over 5-HT1A, 5-HT1D, 5-HT1E, 5-HT2A, 5-HT2C, and 5-HT3 receptors. Exhibits anxiolytic activity upon systemic administration in vivo.
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| BCC5753 | MRS 1334 |
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Potent and highly selective antagonist for the human adenosine A<sub>3</sub> receptor. K<sub>i</sub> values are 2.69 nM at hA<sub>3</sub>, and > 100 <span class='symbol'>μ</span>M at rat A<sub>1</sub> and rat A<sub>2A</sub> receptors.
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| BCC5754 | [Ala11,22,28]VIP |
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Potent and highly selective agonist for the human VPAC1 receptor (Ki values are 7.4 and 2352 nM for binding to human recombinant VPAC1 and VPAC2 receptors respectively).
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| BCC5755 | Ac-RYYRWK-NH2 |
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Potent, selective partial agonist peptide for the NOP receptor (K<sub>i</sub> = 0.71 nM). Selective over <span class='symbol'>μ</span>, <span class='symbol'>δ</span> and <span class='symbol'>κ</span> opioid receptors (IC<sub>50</sub> > 4000 nM). Increases food intake <em>in vivo</em>.
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| BCC5756 | Noladin ether |
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Endogenous agonist for the GPR55 and CB<sub>1</sub> receptors (EC<sub>50</sub> values are 10 and 37 nM respectively) that displays selectivity over CB<sub>2</sub> receptors (K<sub>i</sub> values are 21.2 nM and > 3mM at CB<sub>1</sub> and CB<sub>2</sub> respectively). Causes sedation, hypothermia, intestinal immobility and mild antinociception <em>in vivo</em>. Attenuates sensory neurotransmission in rat mesenteric arteries via GPR55.
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| BCC5757 | Naloxone benzoylhydrazone |
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Mixed opioid receptor agonist/antagonist. Acts as a potent and full agonist at <span class='symbol'>κ</span>, a partial agonist at <span class='symbol'>μ</span> and <span class='symbol'>δ</span> opioid receptors (pEC<sub>50</sub> values are 9.45, 8.74 and 8.61 in a cAMP assay, 9.70, 8.59 and 8.49 in a [<sup>35</sup>S]GTP<span class='symbol'>γ</span>S binding assay respectively). Fails to exert agonist effects at NOP receptors and antagonizes agonist-induced NOP activation. Stimulates <span class='symbol'>κ</span>-, <span class='symbol'>μ</span>- and <span class='symbol'>δ</span>-mediated analgesia and blocks NOP-induced supraspinal nociception.
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