Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1393 - 1400 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5791 | CRF (6-33) |
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Corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.
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| BCC5792 | Sauvagine |
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Corticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b respectively.
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| BCC5793 | [Orn8]-Urotensin II |
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Inhibitor of glycogen synthase kinase-3 (GSK-3); derived from
FRAT1, the mammalian version of GSK-3-binding protein. Binds to GSK-3, inhibiting its interaction with axin, and also blocks GSK-3-catalyzed phosphorylation of axin and β-catenin. Does not affect GSK-3-mediated phosphorylation of glycogen synthase or eIF2B. |
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| BCC5794 | 2-Methylthioadenosine diphosphate trisodium salt |
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Potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13). Induces aggregation of, and inhibits cAMP accumulation in, platelets in vitro.
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| BCC5795 | Y-29794 oxalate |
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Inhibitor of prolyl endopeptidase, a serine peptidase that may be implicated in the biosynthesis of amyloid <span class='symbol'>β</span>-peptide. Potently inhibits rat brain prolyl endopeptidase (K<sub>i</sub> = 0.95 nM) <em>in vitro</em>, and prevents amyloid <span class='symbol'>β</span>-peptide deposition <em>in vivo</em>. Orally active and brain penetrant.
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| BCC5796 | Urotensin II (human) |
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Potent endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Displays arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo, effects which vary between species. Also has been shown to mediate bronchoconstriction.
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| BCC5797 | BAM 22P |
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Potent endogenous agonist peptide for the newly identified sensory neuron specific receptor (SNSR); isolated from bovine adrenal medulla. EC50 values are 13 and 16 nM for human SNSR3 and SNSR4 respectively. Also potent opioid agonist (IC50 = 1.3 nM in guinea pig ileum preparation). Produces opioid- and non-opioid receptor mediated antinociceptive effects in vivo.
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| BCC5798 | BW 373U86 |
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Potent, selective non-peptide <span class='symbol'>δ</span>-opioid receptor agonist. K<sub>i</sub> values are 1.8, 15 and 34 nM for <span class='symbol'>δ</span>, <span class='symbol'>μ</span> and <span class='symbol'>κ</span> receptors respectively. Centrally active following systemic administration <em>in vivo</em>.
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