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Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No.	Product Name
BCN3104	11-Hydroxycanthin-6-one
11-Hydroxy-canthin-6-one has antineoplastic activity.
BCN3105	9-Hydroxycanthin-6-one
1. 9-Hydroxycanthin-6-one inhibits Wnt signaling through the activation of GSK3β independent of CK1α. 2. 9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilization.
BCN3106	9,10-Dimethoxycanthin-6-one
9,10-Dimethoxycanthin-6-one shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 5.0 microM).
BCN3108	Eurycomalactone
1. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)]. 2. Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. 3. Eurycomalactone displays antiplasmodial activity against Gombak A isolate.
BCN3111	Pelargonidin chloride
1. Pelargonidin chloride has anti-diabetic activity. 2. Pelargonidin chloride has antioxidant and anti-inflammatory activities. 3. Pelargonidin chloride is a nitric oxide scavenger, inhibits iNOS protein and mRNA expression and also NO production in a dose-dependent manner.
BCN3112	Pelargonidin-3-O-rutinosde chloride
1. Pelargonidin 3-Rutinoside exhibits antioxidant and anti-inflammatory properties.
BCN3113	Pelargonidin-3-O-glucoside chloride
1. Pelargonidin-3-O-glucopyranoside has antioxidant and anti-inflammatory activities. 2. Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. 2. Pelargonidin-3-O-glucopyranoside exerts potential anti-estrogenic, and angiotensin-converting enzyme inhibitory activities.
BCN3114	Cyanidin-3-O-rutinoside chloride
1. Cyanidin-3-O-rutinoside chloride has antioxidant activity. 2. Cyanidin-3-O-rutinoside chloride improves vision in humans (for night blindness). 3. Cyanidin-3-O-rutinoside chloride has LPO inhibition at a 0.25 μM concentration, inhibits the COX-1 enzyme by 45.2 and COX-2 by 61.5 at 5 μM.