Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3081 | 30-Hydroxygambogic acid |
| 1. 30-Hydroxygambogic acid exhibits significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines. | |
| BCN3083 | Wilfordine |
| 1. Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect. | |
| BCN3085 | Wilfortrine |
| Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression. The combined treatment using wilfortrine and paclitaxel can inhibit proliferation and invasion of liver cancer cells via down-regulating Bcl-2 and up-regulating Bax, with better efficacy than single use of either drug. Wilfortrine and euonine (40.80 mg/(kg.d) x 4d ip) show marked depressant effects on humoral mediated immunity using the hemolysin reaction as indices. | |
| BCN3087 | Evonine |
| Evonine shows insecticidal activity against Mythimna separata, the LC50 value of 23.23 mg /mL. | |
| BCN3088 | Asperulosidic acid |
| 1. Asperulosidic acid has been recently used in chinese medicine as a useful drug against some tumors. 2. Asperulosidic acid has anticlastogenic activity, since the anticlastogenic irridoids have an alpha-unsaturated carbonyl group, this structure is considered to play an important role in the anticlastogenicity. 3. Asperulosidic acid, and 6-O-(beta-D-glucopyranosyl)-1-O-octanoyl-beta-D-glucopyranose are effective in suppressing 12-O-tedtradecanoylphorbol-13-acetate (TPA)- or epidermal growth factor (EGF)-induced cell transformation and associated AP-1 activity. 4. Asperulosidic acid can inhibit the seed germination and growth of seedlings of large crabgrass. | |
| BCN3089 | Digitolutein |
| 1. Digitolutein, extracted from the stem bark and the roots of Morinda lucida Benth., has inhibition on the growth of Plasmodium falciparum in vitro. | |
| BCN3090 | 2-(Hydroxymethyl)anthraquinone |
| 1. 2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc. | |
| BCN3091 | 2-Hydroxy-1-methoxyanthraquinone |
| 1. 2-Hydroxy-1-methoxy- anthraquinone can promote osteoblast proliferation, and can inhibit osteoclast TRAP activity and bone resorption, suggests that it has antiosteoporotic activity. | |
