Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1369 - 1376 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5767 | Ghrelin (rat) |
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Endogenous agonist peptide for the ghrelin receptor (GHS-R1a). Produced mainly by the stomach, it stimulates release of growth hormone from the pituitary gland in vitro and in vivo, and regulates feeding, growth and energy production.
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| BCC5768 | Proglumide sodium salt |
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Non-selective cholecystokinin (CCK) antagonist. Inhibits CCK-stimulated amylase secretion and prevents CCK-induced 2-deoxyglucose uptake in mouse pancreatic acini. Blocks growth of HT29 colon carcinoma cells in response to gastrin 17 treatment. Orally active.
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| BCC5769 | (-)-5'-DMH-CBD |
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Anandamide membrane transport inhibitor (IC<sub>50</sub> = 14 <span class='symbol'>μ</span>M) that is relatively metabolically stable. Displays some affinity for CB<sub>2</sub> receptors but has only weak affinity for CB<sub>1</sub> receptors and has no activity at VR1 receptors or FAAH. Anticonvulsive <em>in vivo</em> following systemic administration.
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| BCC5770 | tcY-NH2 |
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Selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
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| BCC5771 | LY 233053 |
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Competitive NMDA receptor antagonist (IC<sub>50</sub> = 7 nM) that displays no affinity for AMPA or kainate receptors at a concentration of 10 <span class='symbol'>μ</span>M. Inhibits NMDA-induced neuronal degeneration and protects from NMDA-induced convulsions in neonatal rats.
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| BCC5772 | LY 288513 |
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Selective CCK2 receptor antagonist (IC50 values are 16 and > 30,000 nM for CCK2 and CCK1 respectively). Displays anxiolytic and antipsychotic properties in vivo.
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| BCC5773 | 10Z-Hymenialdisine |
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Pan kinase inhibitor (IC<sub>50</sub> values are 6, 10, 22, 28, 35, 40, 70, 80, 100, 470, 500, 600, 700 and 700 nM for MEK1, GSK-3<span class='symbol'>β</span>, Cdk1/cyclin B, Cdk5/p25, CK1, Cdk2/cyclin A, Cdk2/cyclin E, ASK-<span class='symbol'>γ</span>, Cdk3/cyclin E, Erk1, PKC<span class='symbol'>γ</span>, Cdk4/cyclin D1, Cdk6/cyclin D2 and PKC<span class='symbol'>α</span> respectively.) Inhibits NF-<span class='symbol'>κ</span>B activation and blocks IL-8 production in U937 cells (IC<sub>50</sub> values are 1-2 and 0.34-0.48 <span class='symbol'>μ</span>M respectively).
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| BCC5774 | Hemokinin 1 (mouse) |
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Novel mammalian endogenous peptide, homolog of substance P, that is a high affinity and selective agonist at the tachykinin NK1 receptor (Ki values are 0.175 and 560 nM for NK1 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
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