Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3069 | Gambogin |
| 1. Gambogin is a cytotoxic xanthone. | |
| BCN3071 | Gaudichaudic acid |
| 1. Gaudichaudic acid shows cytotoxicities against human leukemia K562 (K562/S) and doxorubicin-resistant K562 (K562/R) cell lines, and shows similar inhibitory effects on both cell lines. | |
| BCN3073 | Morellic acid |
| 1. Morellic acid has cytotoxic activity. 2. Morellic acid has anti-HIV-1 activity. 3. Morellic acid has antibacterial activity. | |
| BCN3074 | Isomorellic acid |
| 1. Isomorellic acid is a cytotoxic caged xanthone. | |
| BCN3075 | Isomorellinol |
| 1. Isomorellinol induces apoptosis in cholangiocarcinoma (CCA)cells which is mediated through a mitochondria-dependent signaling pathway. | |
| BCN3076 | Isogambogenic acid |
| 1. Isogambogenic acid inhibits angiogenesis and may be a viable drug candidate in anti-angiogenesis therapy. 2. Isogambogenic acid exhibits an anticancer effect by inducing autophagy-dependent cell death in NSCLC cells, which may be an effective chemotherapeutic agent that can be used against NSCLC in a clinical setting. | |
| BCN3077 | Gambogenic acid |
| Gambogenic acid is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects, it can cause aberrant autophagy to induce cell death and may suggest the potential application of Gambogenic acid as a tool or viable drug in anticancer therapies.Gambogenic acid could inhibit the proliferation of melanoma B16 cells and induce their apoptosis within certain time and concentration ranges. Its mechanism in inducing the cell apoptosis may be related to PI3K/Akt/mTOR signaling pathways. | |
| BCN3078 | Isogambogic acid |
| 1. Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines. | |
