Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3148 | Delphinidin-3-sambubioside chloride |
| 1. Delphinidin-3-sambubioside chloride has antioxidant activity. 2. Delphinidin-3-sambubioside might induce apoptosis in HL-60 cells through a ROS-mediated mitochondrial dysfunction pathway. | |
| BCN3149 | Quercetin-3-O-glucuronide |
| Quercetin-3-O-glucuronide is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. Quercetin-3-O-glucuronide significantly improves Alzheimer's disease (AD)-type deficits in hippocampal formation basal synaptic transmission and long-term potentiation, possibly through mechanisms involving the activation of the c-Jun N-terminal kinases and the mitogen-activated protein kinase signaling pathways. Quercetin-3-O-glucuronide is equally effective in inhibiting ROS-associated inflammation and ameliorating insulin resistant endothelial dysfunction by beneficial regulation of IRS-1 function. | |
| BCN3150 | Cyanidin-3-O-sambubioside chloride |
| 1. Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NFκB activity. 2. Cyanidin-3-O-sambubioside chloride inhibits the enzyme activity by competing with the substrate for the active site. 3. Cyanidin-3-O-sambubioside chloride has antioxidant activity and free-radical-scavenging property. 4. Cyanidin-3-O-sambubioside chloride is highly water-soluble and is easily degraded by hydrolysis and /or hydrogenation at temperatures >40°C. | |
| BCN3151 | 1,2-Benzenedicarboxylic acid |
| 1. 1,2-Benzenedicarboxylic acid is one kind of allelochemical shows stronger allelopathic effect on itself than on wheat and pigeonpea. 2. 1,2-Benzenedicarboxylic acid has antimicrobial activity. 3. 1,2-Benzenedicarboxylic acid shows anti-extended-spectrum beta-lactamases (ESBL) activity. | |
| BCN3152 | 20-Deoxocarnosol |
| 1. 20-Deoxocarnosol , the main phenolic abietane present in aerial parts of the Chilean medicinal plant, has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH). 2. 20-Deoxocarnosol exhibits non-specific antiprotozoal activity due to high cytotoxicity. | |
| BCN3154 | 6-Hydroxysugiol |
| 1. 6-Hydroxysugiol inhibits proliferation and migration of HepG2 cells and exhibits potent anti-angiogenic activity. | |
| BCN3155 | Ferruginol |
| 1. Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic activities. 2. Ferruginol has cardioprotective, anti-oxidative and anti-inflammatory activities. 3. Ferruginol has anticancer activity, can induce apoptosis in non-small cell lung cancer (NSCLC) cells. 4. Ferruginol has antimicrobial and antifungal activities against wood-rot fungi (basidiomycetes), can cause cellular dysfunction and damage, lead to growth inhibition and autophagic cell death of fungi. | |
| BCN3156 | Methylenetanshinquinone |
| 1. Methylenetanshinquinone has antioxidative activity. 2. Methylenetanshinquinone ranges from 4.1 μM to over 30 μM against P. falciparum K1 strain with selectivity indices (SI) from 0.3 to 1.9. IC50s against T. brucei rhodesiense STIB 900 is from 0.5 μM (1, 4) to over 30 μM, shows the greatest selective activity with an SI of 24. | |
