Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3215 | Salvinolone |
| 1. Salvinolone, demethyl cryptojaponol and taxodione show potent activity with 4-10 microg/mL of MIC against MRSA and 4-16 microg/mL of MIC against VRE. | |
| BCN3218 | 6,7-Dehydroferruginol |
| 1. 6,7-Dehydroferruginol has potent activity against F. palustris . 2. 6,7-Dehydroferruginol and sugiol are weakly active against Heterosigma akashiwo. | |
| BCN3221 | Methylenedihydrotanshinquinone |
| 1. Methylenedihydrotanshinquinone has cytotoxic activity. | |
| BCN3222 | Miltipolone |
| 1. Miltipolone possibly acts as a Fe(2+) chelator to conduct its inhibitory activity. 2. Miltipolone is a good and broad-spectrum inhibitor against the growth of cancer cells. | |
| BCN3224 | Voacangine |
| 1. Voacangine is a novel transient receptor potential vanilloid type 1 (TRPV1) antagonist. 2. Voacangine shows mod. cytotoxic activity, also some CNS, brachycardial and hypotensive action. 3. Voacangine significantly suppresses in vitro angiogenesis, such as VEGF-induced tube formation and chemoinvasion. 4. Voacangine competitively inhibits the binding of menthol to TRPM8 (IC50, 9 μM), but it shows noncompetitive inhibition against icilin (IC50, 7 μM), it may contribute to the development of a novel class of stimulus-selective TRPM8 blockers. | |
| BCN3226 | Kusunokinin |
| 1. Kusunokinin displays significant activity against intracellular amastigotes (IC(50) = 17 µM) and trypomastigotes (IC(50) = 51 µM) without hemolytic activity. | |
| BCN3227 | (-)-Hinokinin |
| 1. (-)-Hinokinin has anti-genotoxic and anticarcinogenic potential. 2. (-)-Hinokinin may serve as a tool to develop new therapeutic drugs for attention deficit hyperactivity disorder. 3. (-)-Hinokinin is an anti-chagasic drug, has no mutagenic effects in animal cell and bacterial systems, anxiety that target the DAT, NET, and GAT-1 transporters. | |
| BCN3229 | Daphnenone |
| 1. Daphnenone shows cytotoxic activity against the tumor cells of human melanoma A375-S2 , with the IC(50) value of 29.8 uM. | |
