Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1473 - 1480 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5872 | NTR 368 |
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Peptide fragment corresponding to residues 368-381 of the human p75 neurotrophin receptor (p75NTR). Forms a helical structure in the presence of micellar lipid. Induces apoptosis in human neuroblastoma cells in vitro.
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| BCC5873 | CALP1 |
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Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM). Shown to protect pancreatic acinar cells from gossypol (Cat.No. 1964) induced necrosis. Inhibits VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo.
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| BCC5874 | Oxyntomodulin |
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Endogenous glucagon-like peptide that modulates feeding and metabolism; secreted by intestinal L-cells. Increases cAMP production and inhibits gastric acid secretion in rat stomach.
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| BCC5875 | Salvinorin A |
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Potent naturally occuring non-nitrogenous κ-opioid selective agonist that displays high affinity at both native (Ki = 4.3 nM) and cloned (Ki = 16 nM) κ-opioid receptors. Also exhibits allosteric modulation of μ-opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties..
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| BCC5876 | Xenin 8 |
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C-Terminal fragment of xenin, a neurotensin-like peptide; modulates pancreatic insulin and glucagon secretion/effects. Stimulates basal and arginine-induced insulin secretion and potentiates the insulin response to glucose (EC50 = 0.16 nM). Also potentiates arginine- and carbachol-induced glucagon secretion in a somatostatin-independent manner.
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| BCC5877 | [Ala11,D-Leu15]-Orexin B |
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Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.
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| BCC5878 | ZD 2079 |
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<span class='symbol'>β</span><sub>3</sub>-adrenoceptor agonist. Relaxes rat mesenteric artery and isolated aorta <em>in vitro</em>. Inhibits ob gene expression and circulating leptin levels in lean mice <em>in vivo</em>.
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| BCC5879 | MRS 2365 |
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Highly potent, selective P2Y<sub>1</sub> receptor agonist (EC<sub>50</sub> = 0.4 nM). Displays no activity at P2Y<sub>12</sub> receptors and only very low agonist activity at P2Y<sub>13</sub> receptors (at concentrations up to 1 <span class='symbol'>μ</span>M). Increases the upregulation of NTPDase1 by ATP<span class='symbol'>γ</span>S.
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