Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3245 | Jacoumaric acid |
| 1. Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor. | |
| BCN3248 | Rubrisandrin A |
| 1. Rubrisandrin A is an anti-HIV agent. | |
| BCN3252 | Baicalin methyl ester |
| 1. Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT). | |
| BCN1517 | Chrysin 6-C-arabinoside 8-C-glucoside |
| 1. Chrysin-6-C-arabinosyl-8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α-glucosidase inhibitors, α-glucosidase inhibitors are widely used in the treatment of type 2 diabetes. | |
| BCN3254 | (-)-Pinoresinol |
| 1. Pinoresinol (PIN)can ameliorate CCl4-induced acute liver injury, and this protection is likely due to anti-oxidative activity and down-regulation of inflammatory mediators through inhibition of NF-kappaB and AP-1. 2. (+)-Pinoresinol possesses fungicidal activities and therapeutic potential as an antifungal agent for the treatment of fungal infectious diseases in humans. 3. Pinoresinol is the precursor of other dietary lignans that are present in whole-grain cereals, legumes, fruits, and other vegetables, PIN can cause an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, suggests that this could be a mechanism by which PIN reduces proliferation and induces differentiation on HL60 cells. | |
| BCN3256 | Licoflavone C |
| 1. Licoflavone C has cytotoxic effect . 2. Licoflavone C has antioxidative effect. 3. Licoflavone C has protective effect toward the chromosome damage induced by DAU or MMC in cultured human peripheral lymphocytes. 4. Licoflavone C exhibits a dose-dependent antagonistic activity at concentrations up to 10−4 M, but stimulates β-galactosidase expression at higher concentrations resulting in a U-shaped-like dose-response curve. | |
| BCN3257 | Ganoderic acid C6 |
| Ganoderic acid C6 has antinociceptive activity. | |
| BCN3260 | Chebulic acid |
| 1. Chebulic acid at both doses (25 and 50 mg/kg) improves biochemical alterations caused by renal ischemia in diabetic rats. 2. Chebulic acid has effects against the progression of AGE-induced endothelial cell dysfunction, may constitute a promising intervention agent against diabetic vascular complications. 3. Chebulic acid significantly reduced the tert-butyl hydroperoxide (t-BHP)-induced cell cytotoxicity, intracellular reactive oxygen species level, and the ratio of GSSH, oxidized form of glutathione (GSH) to the over total GSH (GSH + GSSG) (4.42%) as compared to that with t-BHP alone (8.33%). | |
