Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1457 - 1464 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5855 | N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide |
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Phosphopeptide; binds to the src SH2 domain.
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| BCC5856 | PR 39 (porcine) |
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Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of I<span class='symbol'>κ</span>B<span class='symbol'>α</span>.
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| BCC5857 | L-670,596 |
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Potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist (IC50 = 5.5 nM). Inhibits U-44069-induced contractions of guinea pig trachea (pA2 = 9.0) and human platelet aggregation in vitro (IC50 = 6.5 nM). Also prevents thromboxane-mediated endothelial cell death. Orally active in vivo.
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| BCC5858 | Antagonist G |
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Substance P analog that is a broad spectrum neuropeptide antagonist and antiproliferative agent. Blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. Inhibits neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro; activates JNK and stimulates apoptosis. Inhibits growth of SCLC xenografts in mice in vivo.
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| BCC5859 | Norketamine hydrochloride |
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Major metabolite of ketamine that is a potent non-competitive NMDA receptor antagonist (K<sub>i</sub> = 3.6 <span class='symbol'>μ</span>M for displacement of [<sup>3</sup>H]-MK 801 in rat brain). Antinociceptive and anesthetic <em>in vivo</em>.
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| BCC5860 | 6-Iodonordihydrocapsaicin |
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Potent competitive vanilloid TRPV1 (VR1) receptor antagonist (IC50 = 10 nM). Inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro.
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| BCC5861 | 740 Y-P |
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Cell-permeable phosphopeptide activator of PI 3-kinase. Binds with high affinity to p85 subunit of the enzyme. Displays mitogenic activity in C2 muscle cells and promotes survival of rat cerebellar granule neurons in vitro.
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| BCC5862 | Nogo-66 (1-40) |
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Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth in vitro. Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury in vivo.
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