Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1481 - 1488 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5880 | MRS 2279 |
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Selective, high affinity competitive antagonist of the P2Y1 receptor (Ki = 2.5 nM; IC50 = 51.6 nM). Fails to block nucleotide signaling at most other P2Y receptors (P2Y2, P2Y4, P2Y6, P2Y11 and P2Y12) and potently inhibits ADP-induced aggregation of human blood platelets in vitro (pKB = 8.05).
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| BCC5881 | MRS 2500 tetraammonium salt |
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Highly potent and selective antagonist of the platelet P2Y<sub>1</sub> receptor (K<sub>i</sub> = 0.78 nM). Inhibits ADP-induced aggregation of human platelets with an IC<sub>50</sub> value of 0.95 nM. Inhibits the upregulation of NTPDase1 by ATP<span class='symbol'>γ</span>S. Prevents thrombus formation <em>in vivo</em>.
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| BCC5882 | BVD 10 |
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Highly selective NPY Y1 receptor antagonist. Ki values are 25.7, 1420, 2403 and 7100 nM at Y1, Y2, Y4 and Y5 receptors respectively. Devoid of agonist activity at Y4 receptors.
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| BCC5883 | PDZ1 Domain inhibitor peptide |
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Novel cyclic peptide that disrupts interaction between GluK2 (formerlyy GluR6) and the postsynaptic density protein 95 (PSD-95). Competes with the C-terminus of GluK2 for binding to the PDZ1 domain of PSD-95. Inhibits clustering of kainate receptors.
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| BCC5884 | Urotensin II-related peptide |
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Potent endogenous agonist for the urotensin-II (UT) receptor. Binds with high affinity and potently activates recombinant rat and human UT receptors (EC50 values are 0.55 and 4.8 nM respectively). Produces hypotensive effects following systemic administration in rats.
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| BCC5885 | des-His1-[Glu9]-Glucagon (1-29) amide |
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Glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitro. Blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats.
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| BCC5886 | Rac1 Inhibitor W56 |
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Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. Control peptide available.
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| BCC5887 | Rac1 Inhibitor F56, control peptide |
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Control peptide version of Rac1 Inhibitor W56; comprises residues 45-60 of Rac1 with Trp<sup>56</sup> replaced by Phe. Does not affect GEF-Rac1 interaction.
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