Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3178 | Murrayanol |
| 1. Murrayanol has antioxidant activity. 2. Murrayanol shows an IC50 of 109 μg/mL against hPGHS-1 and an IC50 of 218 μg/mL against hPGHS-2 in antiinflammatory assays. | |
| BCN3181 | Campesterol |
| Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory effect, it inhibits several pro-inflammatory and matrix degradation mediators typically involved in osteoarthritis- induced cartilage degradation, also sometimes used to treat some specific prostate conditions. | |
| BCN1492 | 7-Hydroxy-beta-carboline-1-propionic acid |
| 1. 7-Hydroxy-beta-carboline-1-propionic acid shows cytotoxic activity. | |
| BCN3183 | Platycodigenin |
| 1. Platycodigenin has in vitro anti-proliferative activity against the HSC-T6 cell line. | |
| BCN1452 | 3-beta-O-(trans-p-Coumaroyl)maslinic acid |
| 1. 3-beta-O-(trans-p-Coumaroyl)maslinic acid is a DNA polymerase B" inhibitor. 2. 3-beta-O-(trans-p-Coumaroyl)maslinic acid is a bleomycin cytotoxicity potentiator. | |
| BCN3185 | Schisanlactone A |
| 1. Schisanlactone A shows cytotoxicity against KB (a human epidermal carcinoma) cells with the IC50 value of 63.3 uM. 2. Schisanlactone A is a dimerization inhibitor, with an IC50 value of 5.0 microg/mL. 3. Schisanlactone A shows appreciable inhibitory activity against HIV-1 protease with the IC50 value of 20 microM. | |
| BCN3187 | Viscidulin II |
| 1. Viscidulin II can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates; suggests that it can be potential therapeutic agents against P. acnes-induced skin inflammation. | |
| BCN1293 | 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone |
| 1. 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects on ATPase from the cell. | |
