Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 1497 - 1504 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCC5896 MNI-caged-D-aspartate
D-aspartate caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Photolyzed by UV light with a quantum efficiency of 0.09 at pH 7.4. Agonist at NMDA receptors and EAAT substrate.
BCC5897 Tabimorelin hemifumarate
Potent, orally active ghrelin receptor (GHS-R1a) agonist (K<sub>i</sub> = 50 nM at human recombinant GHS-R1a). Stimulates GH release from rat pituitary cells with an EC<sub>50</sub> value of 2.7 nM. Induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats.
BCC5898 CALP2
Cell-permeable calmodulin (CaM) antagonist that binds to the EF-hand/Ca2+-binding site. CALP2 has been demonstrated to inhibit CaM-dependant phosphodiesterase activity and increase intracellular Ca2+ concentrations by modulating Ca2+-channel activity. CALP2 has also been shown to be a potent activator of alveolar macrophages.
BCC5899 TCS 184
Scrambled control peptide for use with TCS 183.
BCC5900 CALP3
Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca<sup>2+</sup>-binding site. Activates phosphodiesterase in the absence of Ca<sup>2+</sup> and inhibits Ca<sup>2+</sup>-mediated cytotoxicity and apoptosis (IC<sub>50</sub> = 33 <span class='symbol'>&mu;</span>M).
BCC5901 BTS 54-505 hydrochloride
Potently active primary amine metabolite of sibutramine, exhibits a similar pharmacological profile to the parent compound. Inhibits serotonin and noradrenalin reuptake more potently than sibutramine <em>in vitro</em>. Reduces food intake in rodents following i.c.v. administration and increases energy expenditure via thermogenesis <em>in vivo</em>.
BCC5902 (+)-Igmesine hydrochloride
Selective <span class='symbol'>&#963;</span><sub>1</sub> receptor ligand (K<sub>D</sub> = 19.1 nM), with little or no activity at <span class='symbol'>&#963;</span><sub>2</sub> receptors (IC<sub>50</sub> &#62; 1000 nM). Inhibits the NMDA-induced increase in cGMP in a concentration-dependent manner (IC<sub>50</sub> value is approximately 100 nM). Weak inhibitor of brain 5-HT uptake <em>in vitro</em>. Exhibits neuroprotective and antidepressant effects.
BCC5903 Bombinakinin-GAP
Bioactive bradykinin-related peptide. Induces a 60% reduction in food intake following i.c.v. administration in rats.