Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1513 - 1520 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5912 | Obestatin (rat) |
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Endogenous peptide derived from the same prepropeptide as ghrelin</a>. Reported to suppress food intake and reduce body weight-gain in rats.
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| BCC5913 | CH 275 |
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Potent somatostatin receptor 1 (sst<sub>1</sub>) agonist; displays selectivity for sst<sub>1</sub> (IC<sub>50</sub> values are 30.9 nM, 345 nM, > 1 <span class='symbol'>μ</span>M, > 10 <span class='symbol'>μ</span>M and > 10<span class='symbol'>μ</span>M for human sst<sub>1</sub>, sst<sub>3</sub>, sst<sub>4</sub>, sst<sub>2</sub> and sst<sub>5</sub> respectively). Attenuates somatostatin release in the rat nucleus accumbens.
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| BCC5914 | ER 27319 maleate |
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Selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc<span class='symbol'>ε</span>RI in rat and human mast cells. Results in the abrogation of degranulation, TNF-<span class='symbol'>α</span> production (IC<sub>50</sub> = 10 <span class='symbol'>μ</span>M) and other related signaling events.
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| BCC5915 | Bay 36-7620 |
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Selective mGlu<sub>1</sub> receptor non-competitive antagonist (IC<sub>50</sub> = 0.16 <span class='symbol'>μ</span>M) with inverse agonist activity. Impairs classical conditioning and associated synaptic plasticity in hippocampal neurons. Exhibits neuroprotective and anticonvulsive effects <em>in vivo</em> following systemic administration.
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| BCC5916 | CGS 35066 |
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Potent endothelin-converting enzyme (ECE) inhibitor that displays > 100-fold selectivity over neutral endopeptidase 24.11 (IC50 values are 22 and 2300 nM respectively). Blocks the hypertensive effects induced by big ET-1 in vitro and reduces the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH).
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| BCC5917 | UFP 803 |
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Urotensin-II (UT) receptor ligand; behaves as a silent antagonist in most in vitro assays and in vivo, but does retain small residual agonist activity under certain conditions in some assays. Competitively antagonizes U-II induced contractions in the rat aorta (pIC50 = 7.46) and prevents plasma extravasation elicited by U-II in mice in vivo.
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| BCC5918 | PPDA |
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Subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors (K<sub>i</sub> values are 0.096, 0.125, 0.31 and 0.55 <span class='symbol'>μ</span>M for NR2C, NR2D, NR2B and NR2A subunits respectively).
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| BCC5919 | TFB-TBOA |
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Potent and selective glial glutamate transporter EAAT1 and EAAT2 inhibitor (IC50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Has no effect on EAAT4 and EAAT5, or a wide range of neuronal receptors and transporters. Attenuates glutamate-stimulated intracellular Na+ elevation in astrocytes in vitro (IC50 = 43 nM). Induces severe convulsions in vivo.
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