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Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No.	Product Name
BCN3284	4-Nitrobenzyl dimethylcarbamate
1. Carbamic acid with minimum inhibitory concentration (MIC, 5 mg/L) and minimum fungicidal concentration (MFC, 10 mg/L) were against the growth of P. litchi for 2 and 4 days, respectively. 2. Carbamic acid treatment reduced the disease incidence and browning index of litchi fruits, maintained the fruits quality and, thus, it could be an effective postharvest handling to extend the shelf life of litchi fruits during storage.
BCN1601	5'-Geranyl-5,7,2',4'-tetrahydroxyflavone
1. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone inhibits cholinesterase enzyme in a dose-dependent manner against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. 2. 5′-Geranyl-5,7,2′,4′-tetrahydroxyflavone shows better tyrosinase inhibitory activities than kojic acid.
BCN3288	Chlorophorin
1. Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. 2. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM. 3. Chlorophorin can reduce tyrosinase activity and inhibit α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells.
BCN3289	Moracin P
1. Moracin P shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells. 2. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. 3. Moracin P might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells.
BCN3290	Albanin A
1. Albanin A shows mushroom tyrosinase inhibitory activity, the IC50 value is 463 uM. 2. In melanin formation inhibition on B16 melanoma cells, the IC50 of albanin A is 40.1 uM.
BCN3291	Moracin T
1. Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermore can significantly suppress the elevation in 4-HNE level and elevate expression of c-fos, c-myc and cycloxygenase-2 (COX-2) in normal epidermis induced by double application of TPA; the moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
BCN3292	Moracin M
1. Moracin M is a phytoalexin. 2. Moracin M inhibits PDE4D2, PDE4B2, PDE5A1, and PDE9A2 with the IC(50) values of 2.9, 4.5, >40, and >100 μM, respectively.
BCN3293	beta-Rhamnocitrin
1. Beta-Rhamnocitrin is used as a 0.4% aq. soln. for photometric detn. of U (max 505 nm), Th, Fe.