Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1569 - 1576 of 9359 hot products
| Catalog No. | Product Name |
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| BCC5970 | Lorazepam |
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Ligand at the GABA<sub>A</sub> receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.
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| BCC5971 | HU 308 |
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Potent and selective CB<sub>2</sub> receptor agonist (K<sub>i</sub> values are 22.7 nM and > 10 <span class='symbol'>μ</span>M for CB<sub>2</sub> and CB<sub>1</sub> receptors respectively, EC<sub>50</sub> = 5.57 nM). Displays antiallodynic activity in the rat hindpaw incision model of postoperative pain. Also neuroprotective and improves motor performance in a mouse model of Huntington's Disease.
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| BCC5972 | PHA 543613 hydrochloride |
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Potent <span class='symbol'>α</span>7 nAChR agonist that displays selectivity over <span class='symbol'>α</span>3<span class='symbol'>β</span>4, <span class='symbol'>α</span>1<span class='symbol'>β</span>1<span class='symbol'>γδ</span>, <span class='symbol'>α</span>4<span class='symbol'>β</span>2 and 5-HT<sub>3</sub> receptors. Positively influences sensory gating and memory in <em>in vivo</em> models of schizophrenia. Orally active and brain penetrant.
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| BCC5973 | [Ala2,8,9,11,19,22,24,25,27,28]-VIP |
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Highly selective agonist for the VPAC1 receptor (IC50 values are ~ 11.5-13.2 and > 30000 nM for VPAC1 and VPAC2 receptors respectively).
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| BCC5974 | α-Conotoxin ImI |
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Nicotinic receptor antagonist that displays selectivity for homomeric <span class='symbol'>α</span>7 and <span class='symbol'>α</span>9 receptors (IC<sub>50</sub> values are 220 and 1800 nM respectively). Displays no effect on <span class='symbol'>α</span>2<span class='symbol'>β</span>2, <span class='symbol'>α</span>3<span class='symbol'>β</span>2, <span class='symbol'>α</span>4<span class='symbol'>β</span>2, <span class='symbol'>α</span>2<span class='symbol'>β</span>4, <span class='symbol'>α</span>3<span class='symbol'>β</span>3 and <span class='symbol'>α</span>4<span class='symbol'>β</span>4 subunit combinations.
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| BCC5975 | α-Conotoxin AuIB |
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Selective antagonist of <span class='symbol'>α</span>3<span class='symbol'>β</span>4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including <span class='symbol'>α</span>2<span class='symbol'>β</span>2, <span class='symbol'>α</span>2<span class='symbol'>β</span>4, <span class='symbol'>α</span>3<span class='symbol'>β</span>2, <span class='symbol'>α</span>4<span class='symbol'>β</span>2, <span class='symbol'>α</span>4<span class='symbol'>β</span>4 and <span class='symbol'>α</span>1<span class='symbol'>β</span>1<span class='symbol'>γ</span><span class='symbol'>δ</span>.
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| BCC5976 | α-Conotoxin PIA |
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Selective antagonist of <span class='symbol'>α</span>6-containing nicotinic receptors that discriminates between the closely related <span class='symbol'>α</span>6 and <span class='symbol'>α</span>3 subunits (IC<sub>50</sub> values are 0.95 and 74.2 nM for rat <span class='symbol'>α</span>6/<span class='symbol'>α</span>3<span class='symbol'>β</span>2<span class='symbol'>β</span>3 and <span class='symbol'>α</span>3<span class='symbol'>β</span>2 receptors respectively).
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| BCC5977 | Conantokin-T |
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Non-competitive NMDA receptor antagonist (IC<sub>50</sub> = 0.4 <span class='symbol'>μ</span>M). Inhibits Ca<sup>2+</sup> influx and glutamate-induced toxicity in central nervous system neurons. Exhibits age-dependent physiological effects; induces a sleep-like state in young mice and hyperactivity in older mice.
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