Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3444 | Kobophenol A |
| Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-dependent manner, and the IC50 value is 115.8mM. Kobophenol A has protective effect against nitrosative/oxidative or mitochondrial damages resulted in the inhibition of the ROS, intracellular calcium ion level, and mitochondrial transmembrane potential changes on SH-SY5Y cells. | |
| BCN3445 | Hopeachinol B |
| 1. Hopeachinol B is a potent immunosuppressive polyphenol. | |
| BCN3447 | Kurarinol |
| 1. Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. 2. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, is a candidate as skin-whitening agents. | |
| BCN3448 | Kushenol K |
| 1. Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5. 2. Kushenol K has inhibitory effects on diacylglycerol acyltransferase (DGAT). 3. Kushenol K shows weak antiviral activity against Herpes simplex virus types I and II. | |
| BCN3450 | Digiferruginol |
| 1. Digiferruginol has cytotoxic activity. 2. Digiferruginol and hederagenin show weak effect on porcine respiratory and reproductive syndrome virus (PRRSV) with an IC50 value of 80.5 ± 16.9 uM(SI = 19.9) and 43.2 ± 7.4 uM (SI = 13.1), respectively. | |
| BCN3451 | 2-Anthraquinonecarboxylic acid |
| Anthraquinone-2-carboxylic acid is a novel electron shuttling mediator, shows potent anti-inflammatory and antinociceptive activities in vivo, thus contributing to the immune regulatory role of fruits and herbs. | |
| BCN3453 | 1,3,5,6-Tetrahydroxyxanthone |
| 1. 1,3,5,6-Tetrahydroxyxanthone can inhibit angiotensin-I-converting-enzyme activity in a dose-dependent manner. 2. 1,3,5,6-Tetrahydroxyxanthone shows moderate hepatoprotective activity with EC(50) values of 160.2 +/- 0.6 microM against tacrine-induced cytotoxicity in HepG2 cells. | |
| BCN3455 | Alisol A |
| 1. Alisol A presents inhibitory effects on cancer cell lines tested(HepG2, MDA-MB-231, and MCF-7 cells). 2. Alisol A enhances LC3II expression, indicates autophagy is occured, suggests that alisol A may be an autophagic inducer. | |
