Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1665 - 1672 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC6067 | Compstatin control peptide |
|
Control peptide for Compstatin, a complement inhibitor.
|
|
| BCC6068 | MCH (human, mouse, rat) |
|
Potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively). Increases food intake in vivo.
|
|
| BCC6069 | TFM-4AS-1 |
|
Potent selective androgen receptor modulator (SARM) (IC<sub>50</sub> = 30 nM). Steroidal compound. Exhibits limited effects on reproductive tissues and sebaceous glands; does not repress AP-1-sensitive MMP-1 reporter. Inhibits 5<span class='symbol'>α</span>-reductase type I and II (IC<sub>50</sub> values are 2 and 3 nM respectively).
|
|
| BCC6070 | MRK 016 |
|
GABA<sub>A</sub> receptor inverse agonist selective for the <span class='symbol'>α</span>5-subtype (EC<sub>50</sub> = 3 nM). Exhibits affinity at benzodiazepine binding site of recombinant human GABA<sub>A</sub> receptors (K<sub>i</sub> values are 0.77 nM, 0.83 nM, 0.85 nM and 1.4 nM for <span class='symbol'>α</span>3-, <span class='symbol'>α</span>1-, <span class='symbol'>α</span>2-, and <span class='symbol'>α</span>5-containing respectively). Increases long-term potentiation (LTP) in mouse hippocampal slices. Exhibits no anxiogenic or proconvulsant activity.
|
|
| BCC6071 | CD 2314 |
|
Potent and selective RAR<span class='symbol'>β</span> receptor agonist (K<sub>d </sub>values are 145 and >3760 nM for RAR<span class='symbol'>β</span> and RAR<span class='symbol'>α</span> receptors respectively; no binding detected at RAR<span class='symbol'>γ</span>). Inhibits growth of human HNSCC 22B, 183A and 22A cells (IC<sub>50</sub> values are 3.0, 5.7 and 8.0 <span class='symbol'>μ</span>M respectively).
|
|
| BCC6072 | 7,8-Dihydroxyflavone |
|
1. 7,8-Dihydroxyflavone(7,8-DHF) shows anti-inflammatory and anti-oxidant properties, it can be used as a potent facultative ingredient in health-beneficial agents to prevent or treat the skin aging or inflammatory skin disorders.
2. Treatment with 7,8-DHF during the early postnatal period restores the major trisomy-linked neurodevelopmental defects, suggesting that therapy with 7,8-DHF may represent a possible breakthrough for Down syndrome. 3. 7,8-DHF improves mitochondrial respiration in STs from obese women, suggesting that the obese phenotype in the placenta can be rescued by TRKB activation. 4. 7,8-DHF is beneficial for both depression and anxiety-like behaviors, and may exert fast-onset antidepressant effects. 5. 7,8-DHF exhibits anti-melanogenic activity through inhibition of tyrosinase activity in α-MSH-stimulating condition, it also shows anticancer activity in melanoma cells via downregulation of α-MSH/cAMP/MITF pathway. 6. 7,8-DHF ameliorates motor deficits via suppressing α-synuclein expression and oxidative stress in the MPTP-induced mouse model of Parkinson's disease. 7. 7,8-DHF has an anti-obesity effect in vitro, it inhibits adipocyte differentiation via antioxidant activity and induces apoptosis in 3T3-L1 preadipocyte cells. 8. 7,8-DHF has vasorelaxing and antihypertensive effects . |
|
| BCC6073 | RETF-4NA |
|
Chymase substrate peptide that is cleaved more avidly by <span class='symbol'>α</span><sub>2</sub>-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.
|
|
| BCC6074 | TCS 2002 |
|
Potent inhibitor of GSK-3<span class='symbol'>β</span> (IC<sub>50</sub> = 35 nM). Oral adminstration inhibits cold water stress-induced tau hyperphosphorylation in the mouse brain.
|
|