Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1713 - 1720 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6115 | GSK 9027 |
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Glucocorticoid receptor agonist (pIC50 = 8). Inhibits production of the proinflammatory mediator IL-6 in vivo.
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| BCC6116 | SB 772077B dihydrochloride |
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Potent Rho-kinase (ROCK) inhibitor (IC<sub>50</sub> value of approximately 5.6 nM at recombinant human ROCK1 and 2). Decreases pulmonary and systemic arterial blood pressures and increases cardiac output. Exhibits vasodilator activity that is more potent than Y-27632 or Fasudil.
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| BCC6118 | 3-pyr-Cytisine |
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High affinity <span class='symbol'>α</span>4<span class='symbol'>β</span>2 partial agonist (K<sub>i</sub> values are 0.91, 119 and 1100 nM for <span class='symbol'>α</span>4<span class='symbol'>β</span>2, <span class='symbol'>α</span>3<span class='symbol'>β</span>4 and <span class='symbol'>α</span>7 receptors respectively). Shows little activity at <span class='symbol'>α</span>3<span class='symbol'>β</span>4 and <span class='symbol'>α</span>7 receptors. Exhibits antidepressant-like effects in mouse models of antidepressant efficacy.
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| BCC6119 | NPS 2390 |
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Group I mGlu antagonist; displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors. Thought to act on a site separate from the glutamate binding pocket.
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| BCC6120 | Conantokin G |
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GluN2B (formally NR2B) selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM); also inhibits NMDA-evoked responses in oocytes expressing GluN2B (formally NR2B), but not GluN2A (formally NR2A), subunits (IC50 ~300 nM). Exhibits neuroprotective properties in vivo and in vitro.
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| BCC6121 | TMN 355 |
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Potent cyclophilin A inhibitor (IC<sub>50</sub> = 1.52 nM). Approximately 27 times more potent than cyclosporin A.
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| BCC6122 | TCN 201 |
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NMDA receptor antagonist selective for GluN1/GluN2A (formally NR1/NR2A) over GluN1/GluN2B (formally NR1/NR2B) containing receptors (pIC50 values are 6.8 and <4.3, respectively, in human recombinant GluN1/GluN2A (formally NR1/NR2A) and GluN1/GluN2B (formally NR1/NR2B) FLIPR/Ca2+ assays).
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| BCC6123 | TCN 213 |
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NMDA receptor antagonist, selective for GluN1/GluN2A (formally NR1/NR2A) (pIC50 = 5.4) over GluN1/GluN2B (formally NR1/NR2B) containing receptors.
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