Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1753 - 1760 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6157 | Ro 51 |
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Potent, dual P2X<sub>3</sub> and P2X<sub>2/3</sub> antagonist (IC<sub>50</sub> values are 2 and 5 nM for rP2X<sub>3</sub> and hP2X<sub>2/3</sub> respectively). Selective for P2X<sub>3</sub> and P2X<sub>2/3</sub> over other P2X receptors (IC<sub>50</sub> values are > 10 <span class='symbol'>μ</span>M for P2X<sub>1</sub>, P2X<sub>2</sub>, P2X<sub>4</sub>, P2X<sub>5</sub>, and P2X<sub>7</sub>). Cell permeable.
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| BCC6158 | 680C91 |
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Potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) (Ki = 51 nM). Exhibits no activity against indoleamine 2,3-dioxygenase, monoamine oxidase A and B, 5-HT uptake or 5-HT1A, 1D, 2A and 2C receptors. Produces large increases in brain tryptophan and serotonin in vitro and in vivo in the rat.
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| BCC6159 | VU 0360223 |
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Potent negative allosteric modulator of mGlu5 (IC50 = 61 nM). Displays no activity at mGlu1-4 and mGlu7-8.
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| BCC6160 | SC 66 |
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Allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. Exhibits anticancer activity in vitro and in vivo.
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| BCC6161 | (±)-CPSI 1306 |
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Reported to be a macrophage inhibitory factor (MIF) inhibitor.
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| BCC6162 | SMIFH2 |
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Inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation and barbed end elongation. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts.
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| BCC6163 | 26RFa |
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Hypothalamic RFamide-related neuropeptide. Acts as a natural ligand of the orphan receptor GPR103. Exhibits orexigenic acitivity in mice upon central administration.
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| BCC6164 | VU 0365114 |
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Selective positive allosteric modulator of M<sub>5</sub> (EC<sub>50</sub> values are 2.7 <span class='symbol'>μ</span>M for human M<sub>5</sub>, and >30 <span class='symbol'>μ</span>M for M<sub>1</sub>, M<sub>2</sub>, M<sub>3</sub> and M<sub>4</sub> receptors).
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