Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7895 | Uralsaponin D |
| 1. Uralsaponin D displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 μmol/L, it could significantly increase the cytotoxic activity after hydrolysis. | |
| BCN7897 | Licoricesaponin G2 |
| 1. Licoricesaponin G2 has the anti-inflammatory effects as NF-κB inhibitors. 2. Licoricesaponin G2 has anti-HIV activity via significantly interacted with R15K. | |
| BCN7898 | Silybin B |
| 1. Silybin B and silybin A show strong effects on cell growth inhibition and apoptosis induction in human chronic myeloid leukemia K562 cells. 2. Silybin B exhibits 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. 3. Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in all enzyme systems. | |
| BCN7899 | 8-O-Methylretusin-7-O-beta-D-glucopyranoside |
| 1. 8-O-Methylretusin-7-O-beta-D-glucopyranoside shows significant antimicrobial activity with a broad spectrum as well as antioxidant activity . | |
| BCN7900 | Licopyranocoumarin |
| 1. Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane potential, which were mediated by JNK. | |
| BCN7902 | Menisporphine |
| 1. Menisporphine shows cytotoxic activity on the target cancer cell lines. 2. Menisporphine shows significant angiogenesis inhibitions. | |
| BCN7903 | Dauriporphine |
| 1. Dauriporphine shows cytotoxic activity on the target cancer cell lines. 2. Dauriporphine shows significant angiogenesis inhibitions. 3. Dauriporphine shows significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts. 4. Dauriporphine shows potent P-gp MDR inhibition activity with an ED50 value 0.03 microg/mL and 0.00010 microg/mL in the MES-SA/DX5 and HCT15 cells, respectively. | |
| BCN7905 | Licoricesaponin A3 |
| 1. Licoricesaponin A3 shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L. | |
