Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7957 13,18-Dehydroglaucarubinone
1. 13,18-Dehydroglaucarubinone can inhibit growth of the murine lymphocytic leukemia P388.
BCN7959 trans-4-Hydroxy-2-nonenoic acid
1. trans-4-Hydroxy-2-nonenoic acid is a marker of lipid peroxidation resulting from the metabolism of trans-4-hydroxy-2-nonenal . 2. trans-4-Hydroxy-2-nonenoic acid is a gamma-hydroxybutyrate receptor ligand in the cerebral cortex and hippocampus.
BCN7960 Methyl isovanillate
Methyl isovanillate is a natural product from Vitex agnus-castus.
BCN7961 Tenulin
1. Tenulin is a potent antifeedant to the European corn borer Ostrinia nubilalis. 2. Tenulin is an antitumor agent, it can inhibit DNA synthesis and DNA polymerase enzymatic activity in the tumor cells.
BCN7966 Ganoderenic acid B
1. Ganoderenic acid B can enhance the cytotoxicity of chemotherapeutics towards ABCB1-mediated MDR cancer cells via inhibition of the transport function of ABCB1.
BCN7968 Cannabinol
1. Cannabinol activates capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism.
BCN7970 Lucidenic acid C
1. Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
BCN7971 Ganoderic acid X
1. Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). 2. Ganoderic acid X, a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.