Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7973 | 7-Oxo-ganoderic acid Z |
| 1. 7-Oxo-ganoderic acid Z shows strong inhibitory effects against α-glucosidase. 2. 7-Oxo-ganoderic acid Z can reduce cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36 uM. 3. 7-Oxo-ganoderic acid Z exhibits inhibitory activities against the HMG-CoA reductase and acyl CoA acyltransferase. | |
| BCN7974 | 8,9-Dihydroxy-10-isobutyryloxythymol |
| 1. 8,9-Dihydroxy-10-isobutyryloxythymol shows in vitro antibacterial and antifungal effects. | |
| BCN3789 | D-Mannitol busulfan |
| Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake. Mannitol has been used clinically to reduce intracranial pressure with varying success, and it is possible that it is more effective in some types of head injury than in others. | |
| BCN3790 | Isokaempferide |
| 1. Isokaempferide shows anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. 2. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea. 3. The hydroxyflavones (luteolin, apigenin and isokaempferide) exert comparable antiproliferative activities against malignant and normal cells. 4. Isokaempferide shows strong inhibitory effect on TNF-alpha-induced liver cell death with the IC50 value of 22.8 microM, suggests that it has hepatoprotective activity. | |
| BCN3791 | D-Arabinose |
| Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy. | |
| BCN3792 | Ethyl 4-hydroxyphenylacetate |
| Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A. | |
| BCN8611 | Protodeltonin |
| 1. Protodeltonin can inhibit the proliferation of a panel of established human and murine cancer cell lines in vitro. 2. Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. | |
| BCN8582 | Isorosmanol |
| 1. Isorosmanol is a promising natural compound for further studies on development of new medications which might be useful in ageing disorders such as the declining of cognitive functions and hyperpigmentation. 2. Isorosmanol possesses both neuroprotective and neurotrophic effects, that might be beneficial for controlling Alzheimer's disease. 3. Isorosmanol has antioxidant activity. | |
