Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1857 - 1864 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC6262 | KL 001 |
|
Cryptochrome protein (CRY) stabilizer; blocks proteasome-mediated degradation of CRY1 and CRY2. Lengthens circadian period in mouse NIH-3T3 fibroblasts without altering casein kinase activity. Represses glucagon-induced hepatic gluconeogenesis through the induction of Pck1 and G6pc expression.
|
|
| BCC6263 | GSK J2 |
|
Inactive control of GSK J1</a> (Cat No.4593) (IC<sub>50</sub> > 100 <span class='symbol'>μ</span>M for inhibition of JMJD3/UTX). Cell permeable ester derivative, GSK J5, also available.
|
|
| BCC6264 | GSK J5 |
|
Inactive isomer of GSK J4; also cell permeable ester derivative of the inactive control, GSK J2
|
|
| BCC6265 | PU 02 |
|
Negative allosteric modulator of 5-HT<sub>3</sub> receptors (IC<sub>50</sub> values are 0.36 and 0.73 <span class='symbol'>μ</span>M in HEK293 cells transfected with human 5-HT<sub>3A</sub> and 5-HT<sub>3AB</sub> receptors respectively).
|
|
| BCC6266 | LP 20 hydrochloride |
|
Ligand of the 5-HT<sub>7</sub> receptor (K<sub>i</sub> = 2.6 nM); exhibits agonist and antagonist activity. Displays selectivity over adrenergic <span class='symbol'>α</span><sub>1</sub> and 5-HT<sub>1A</sub> receptors (K<sub>i</sub> values are 156 and 476 nM respectively).
|
|
| BCC6267 | TC LPA5 4 |
|
LPA<sub>5</sub> receptor antagonist (IC<sub>50</sub> = 0.8 <span class='symbol'>μ</span>M in LPA<sub>5</sub>-RH7777 cells). Inhibits LPA-induced aggregation of isolated human platelets. Exhibits selectivity for LPA<sub>5</sub> against 80 other screened targets.
|
|
| BCC6268 | PF 06465469 |
|
Potent inhibitor of interleukin-2 inducible T cell kinase (ITK) (IC50 = 2 nM). Also exhibits inhibitory activity against Bruton's tyrosine kinase (BTK) (IC50 = 2 nM). Displays nanomolar potencies in a cell-based IP1 assay and human whole blood assay (IC50 values are 31 and 48 nM respectively).
|
|
| BCC6269 | Hexa-D-arginine |
|
Inhibitor of furin (K<sub>i</sub> values are 0.106, 0.58 and 13.2 <span class='symbol'>μ</span>M for furin, PACE4 and PC1 respectively).
|
|