Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8693 | Isorhamnetin 3-robinobioside |
| 1. Isorhamnetin 3-O-robinobioside has a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562. | |
| BCC8287 | 6,7-Dihydroxy-4-Methylcoumarin |
| 1. 4-Methylesculetin has cytotoxicity. 2. 4-Methylesculetin displays a potent metal chelating agent. 3. 4-Methylesculetin could be an effective agent to treat arthritis and associated secondary complications like oxidative stress. 4. 4-Methylesculetin inhibits pancreatic cancer growth and metastasis by inhibition of hyaluronan synthesis. 5. 4-Methylesculetin has great anti-oxidant and anti-inflammatory activities, it has a promising potentiality to treat inflammatory diseases, especially those related to reactive oxygen species, as inflammatory bowel disease. | |
| BCN8283 | (±)-Galgravin |
| 1. Galgravin has cytotoxic activity against human leukemia (HL-60) tumor cells with the IC50 value of 16.5 ± 0.8 ug/mL. 2. Galgravin can inhibit bone resorption and may offer a novel compounds for the development of drugs to treat bone-destructive diseases such as osteoporosis. 3. Galgravin has neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protect against neuronal death from 1-methyl-4-phenylpyridinium ion (MPP+)-induced toxicity in cultured rat hippocampal neurons. 4. Galgravin displays anti-inflammatory activity. 5. Galgravin has anti-platelet activating factor principles. | |
| BCN8370 | Karanjin |
| 1. Karanjin possesses gastroprotective property. 2. Karanjin possesses significant antioxidant activity. 3. Karanjin has larvicidal activity toward C. pipiens pallens larvae and A. aegypti larvae. 4. Karanjin plays anti-inflammatory role in experimental arthritis model as well as on macrophage signalling. 5. Karanjin is a potent Volume-regulated anion channels(VRACs) current inhibitor, the VRAC inhibition might be responsible for its anti-angiogenic effects. 6. Karanjin has the potential to cure colitis induced by intracolonic administration of 2,4,6-trinitrobenzenesulfonic acid (TNBS). 7. Karanjin can significantly reverse the amnesia induced by diazepam and improve learning and memory of mice in dose and time dependent manner. 8. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis, it may be effective clinically for cancer pharmacotherapy. 9. Karanjin possesses significant antihyperglycemic activity in Streptozotocin-induced diabetic rats and type 2 diabetic db/db mice and protein tyrosine phosphatase-1B may be the possible target for their activity. | |
| BCN3799 | 2-Pentylfuran |
| 2-Pentylfuran is a naturally occuring flavouring ingredient, it may be a biomarker for lung colonization/infection by fungal pathogens. 2-Pentylfuran and isomers of 2-pentenylfuran are known to be mainly responsible for the undesirable reversion flavor of soybean oil. | |
| BCN8648 | Bryodulcosigenin |
| 1. Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction. | |
| BCN3800 | Phenol |
| Phenol, anthocyanin and ascorbic acid have antioxidant capacity. | |
| BCC8180 | Guaiazulen |
| 1. Guaiazulene has antioxidant activity, it shows significant protection against paracetamol-induced GSH depletion and hepatic damage. 2. Guaiazulene shows cytotoxic activity on gingival fibroblasts. 3. Guaiazulene has in vitro antimicrobial activity against Mycoplasma hominis clinical isolates. 4. Guaiazulene has anti-proliferative activity suppressing the proliferation of neuron and N2a-NB cells at high doses. | |
