Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1913 - 1920 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6318 | LUF 6283 |
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Partial agonist of hydroxycarboxylic acid receptor 2 (HCA<sub>2</sub>) (K<sub>i</sub> = 0.55 <span class='symbol'>μ</span>M). Thought to lower plasma very-low-density lipoprotein (VLDL)-triglyceride levels by affecting hepatic VLDL production in normolipidemic C57BL/6 mice.
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| BCC6319 | CU CPT 4a |
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Selective TLR3 inhibitor (IC<sub>50</sub> = 3.44 <span class='symbol'>μ</span>M in RAW 264.7 cells); suppresses downstream signaling pathways mediated by the TLR3/dsRNA complex, inhibiting TNF-<span class='symbol'>α</span> and IL-1<span class='symbol'>β</span> production in whole cells.
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| BCC6320 | CU CPT 22 |
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Selective toll-like receptor 1/2 (TLR1/2) inhibitor (IC<sub>50</sub> = 0.58 <span class='symbol'>μ</span>M). Exhibits no activity at TLR2/TLR6, TLR3, TLR4 and TLR7 or a panel of 10 representative kinases. Inhibits the release of proinflammatory cytokines TNF-<span class='symbol'>α</span> and IL-1<span class='symbol'>β</span>.
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| BCC6321 | CYM 5541 |
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Selective sphingosine-1-phosphate receptor 3 (S1P<sub>3</sub>) allosteric agonist (EC<sub>50</sub> = 72-132 nM). Occupies a different space within the ligand binding pocket of S1P<sub>3</sub> than S1P. Displays no activity at S1P<sub>1</sub>, S1P<sub>2</sub>, S1P<sub>4</sub> and S1P<sub>5</sub> receptors at concentrations up to 10 <span class='symbol'>μ</span>M. Shows no significant activities in a profiling panel of 55 GPCRs, ion channels and transporters.
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| BCC6322 | PF 4778574 |
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Positive allosteric modulator of AMPA receptors (Ki = 85 nM). Prevents ketamine-induced working memory impairments. Brain penetrant.
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| BCC6323 | Optovin |
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Reversible photoactive TRPA1 activator. Stimulates human TRPA1 channels <em>in vitro</em> and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC<sub>50</sub> = 2 <span class='symbol'>μ</span>M) and mice, <em>in vivo</em>.
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| BCC6324 | JW 642 |
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Potent and selective monoacylglycerol lipase (MAGL) inhibitor (IC<sub>50</sub> = 3.7 nM). Displays >1000-fold selectivity for MAGL over fatty acid amide hydrolase (IC<sub>50</sub> = 20.6 μM). Analog of JZL 195.
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| BCC6325 | SN 2 |
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Selective TRPML3 channel activator (EC<sub>50</sub> = 1.13 <span class='symbol'>μ</span>M).
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