Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8695 | Clitorin |
| 1. Clitorin has free radical scavenging property. 2. Clitorin shows significant interactions with CD38, it may have anti-hyperglycemic potential . | |
| BCN3797 | Limonene |
| Limonene has antioxidant activity, it at all concentrations reveal a reduction in the frequency of MN and DNA damage induced by H2O2. | |
| BCN3798 | Kushenol F |
| 1. Kushenol F, kuraridin, sophoraflavanone G, and kurarinone are tyrosinase inhibitors. 2. Kushenol F shows significant inhibitory effects on monoamine oxidase ( in a dose-dependent manner with IC50 values of 69.9 microM). 3. Kushenol F preferentially inhibits the MAO-B activity than MAO-A activity with the IC50 values of 63.1 and 103.7 microM, respectively. | |
| BCC8933 | Deltonin |
| 1. Deltonin may be a potential chemotherapeutic agent against neck squamous cell carcinoma (HNSCC), it can induce both apoptosis and autophagy in head and neck squamous carcinoma FaDu cell. 2. Deltonin exhibits induction effect on platelet aggregation. 3. Deltonin inhibits angiogenesis by regulating VEGFR2 and subsequent signaling pathways in endothelial cells. 4. Deltonin induces apoptosis in MDA-MB-231 human breast cancer cells via reactive oxygen species-mediated mitochondrial dysfunction and ERK/AKT signaling pathways. | |
| BCC1189 | Acitretin |
| 1. Acitretin for chemoprevention of non-melanoma skin cancers in renal transplant recipients. 2. Acitretin dramatically improves the results of UV-B treatment in patients with severe psoriasis and it markedly decreases the effective cumulative UV-B dose. 3. Acitretin in the treatment of severe lichen sclerosus et atrophicus of the vulva. 4. Acitretin therapy is effective for psoriasis associated with human immunodeficiency virus infection. 5. Acitretin has immunomodulatory effect, and low dose acitretin therapy is safe, well tolerated and partially effective in chemoprophylaxis of skin cancer in renal transplant recipients. | |
| BCC8352 | Protogracillin(P) |
| 1. Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis. | |
| BCN8683 | Protohypericin |
| 1. Protohypericin exhibits photocytotoxicity. | |
| BCN8675 | 13-Methylberberine |
| 1. 13-Methylberberine shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug. 2. 13-Methylberberine may reduce circulating HMGB1 levels and increase survival in a mouse model of sepsis by activating AMP-activated protein kinase (AMPK). 3. 13-Methylberberine can be useful as an immunotherapeutic compound for induction of IL-12, which is potentially applicable for tumors, infectious disease, and airway inflammation. | |
